Cross‐sectional and longitudinal associations between body flexibility and sarcopenia

Gao, Peng; Gan, Da; Li, Shanshan; Kang, Qingcong; Wang, Xiaoyan; Zheng, Weifang; Xu, Xiaochen; Zhao, Xueyin; He, Wei; Wu, Joyce; Lü, Ying; Hsing, Ann W.; Zhu, Shankuan

doi:10.1002/jcsm.13157

Cited by 4 publications

(1 citation statement)

References 45 publications

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“…Dual-energy x-ray absorptiometry (DXA) was used to measure fat mass in the whole body, trunk, android, gynoid, and leg regions. 18 Body fat percentage (BFP) was calculated as whole body fat mass divided by weight. Trunk fat mass percentage (TFP), android fat mass percentage (AFP), gynoid fat mass percentage (GFP), and leg fat mass percentage (LFP) were calculated as a percentage of whole body fat mass.…”

Section: Measurement Of Adiposity-related Phenotypesmentioning

confidence: 99%

Eastern Diet - A Healthful Dietary Pattern from Eastern China: Its Characteristics and Relation to Adiposity, Cardiometabolic Diseases, Mortality and Gut Microbiota

Shi,

Kan,

et al. 2024

Preprint

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BackgroundThe dietary pattern along the downstream of the Yangtze River in Eastern China has garnered widespread attention for its potential health benefits; however, population-based evidence is limited. This study aimed to identify and characterize this dietary pattern, develop a dietary pattern index, and evaluate its associations with adiposity, cardiometabolic diseases, mortality, and gut microbiota.MethodsThis study included 8,852 adults aged 18-80 from the WELL-China cohort in Hangzhou, Eastern China, between 2016 to 2019. Dietary intake was assessed using a validated food frequency questionnaire. We adopted K-means clustering to identify the Eastern Diet (EastDiet) pattern within the study population and developed a dietary index to quantify adherence to the EastDiet. Adiposity was characterized by total and regional fat measured via dual-energy x-ray absorptiometry. Incident cardiometabolic diseases were documented through October 2022. In addition, we extrapolated the EastDiet index to a nationwide representative cohort of old individuals, including 13,773 participants of the Chinese Longitudinal Healthy Longevity Survey (CLHLS), followed from 2008 to 2018. Linear regression and Cox proportional models were used to assess the associations of the EastDiet index with the study outcomes.ResultsIn the WELL-China, we identified an EastDiet pattern emphasizing high consumption of plant-based foods and low consumption of refined grains and red meat, aligning with previously reported healthy eating habits in Eastern China. The EastDiet index was constructed based on intake levels of 12 food groups. Higher EastDiet adherence was significantly associated with lower level of overall adiposity (BMI and body fat percentage) and central adiposity (waist-hip ratio and android-gynoid fat ratio), reduced incident cardiometabolic diseases (HRhighv.s,low= 0.65, 95% CI: 0.43-0.97), and higher gut microbial diversity and abundance of beneficial genera. In the CLHLS, individuals living in the eastern regions had higher EastDiet index scores compared to other regions of China. Higher EastDiet adherence was also associated with decreased mortality.ConclusionHigher adherence to the EastDiet was associated with more favorable cardiometabolic outcomes, reduced mortality risk, and improved diversity and taxonomy of gut microbiota. These findings support that the EastDiet identified in this study, could be considered an important healthy dietary pattern for Chinese adults.

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Section: Measurement Of Adiposity-related Phenotypesmentioning

confidence: 99%

Eastern Diet - A Healthful Dietary Pattern from Eastern China: Its Characteristics and Relation to Adiposity, Cardiometabolic Diseases, Mortality and Gut Microbiota

Shi,

Kan,

et al. 2024

Preprint

Self Cite

View full text Add to dashboard Cite

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Cross‐sectional and longitudinal associations between body flexibility and sarcopenia

Gao

Gan

et al. 2022

J cachexia sarcopenia muscle

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BackgroundThe associations between body flexibility and sarcopenia were not well understood. This study aimed to explore the cross-sectional and longitudinal associations of flexibility with sarcopenia. Methods Our study selected participants aged 50-80 from the WELL-China cohort and the Lanxi cohort. Participants from the urban area of the Lanxi cohort were followed up 4 years later. Body flexibility was measured by the sit-andreach test. Muscle mass was evaluated by dual-energy X-ray absorptiometry. Muscle strength was evaluated using handgrip strength. Sarcopenia was defined as having both low muscle mass and low muscle strength. We used multivariable logistic regressions to assess the cross-sectional associations of body flexibility with low muscle mass, low muscle strength and sarcopenia. We also used multivariable logistic regressions to explore the associations of baseline flexibility and 4-year changes in flexibility with incident low muscle mass, low muscle strength and sarcopenia. Results A total of 9453 participants were enrolled in the cross-sectional study, and 1233 participants were included in the longitudinal analyses. In the cross-sectional analyses, compared with low body flexibility, high body flexibility was inversely associated with low muscle mass (odds ratio [OR], 0.58; 95% confidence interval [CI], 0.50-0.68; P < 0.001), low muscle strength (OR, 0.62; 95% CI, 0.55-0.69; P < 0.001) and sarcopenia (OR, 0.52; 95% CI, 0.41-0.65; P < 0.001), and these associations did not differ in different age groups, sex or physical activity levels. In the longitudinal analyses, compared with participants with low body flexibility, participants with high body flexibility had lower risk of the incident low muscle strength (OR, 0.53; 95% CI, 0.38-0.74; P < 0.001) and sarcopenia (OR, 0.36; 95% CI, 0.21-0.61; P < 0.001), but not incident low muscle mass (OR, 0.59; 95% CI, 0.33-1.06; P = 0.076). Every 1cm increase in flexibility during 4 years was associated with reduced risk of incident low muscle mass (OR, 0.96; 95% CI, 0.93-1.00; P = 0.025), low muscle strength (OR, 0.96; 95% CI, 0.94-0.98; P = 0.002) and sarcopenia (OR, 0.96; 95% CI, 0.93-0.99; P = 0.007). ConclusionsHigh flexibility was associated with reduced risk of incident low muscle strength and sarcopenia. Increases in flexibility were associated with reduced risk of incident low muscle mass, low muscle strength and sarcopenia. Flexibility exercises and monitoring the dynamic change of flexibility might be helpful in preventing sarcopenia among adults aged 50 years or over. Keywords change in flexibility; change in muscle mass and muscle strength; muscle mass; muscle strength; sit-and-reach test

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Physiotherapy Management combined with Blood Flow Restriction: A single case study

Fuhad,

Zahari,

Justine

et al. 2024

E-BPJ

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The optimum long-term treatment for patellofemoral pain is uncertain, although current assessments and treatments emphasize physiological functioning and education above biological or tissue pathology. The 27-year-old man experienced patellofemoral pain for four years despite little physiotherapy management. Many doctors urged him to avoid excessive exertion, stopping him from enjoying sports. A month of 12 physiotherapy management and Blood Flow Restriction treatments reduced the patient's symptoms by 1%. This case study highlights the necessity for more significant research on patellofemoral pain workouts with physiotherapy and blood flow constraints.

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Cross‐sectional and longitudinal associations between body flexibility and sarcopenia

Cited by 4 publications

References 45 publications

Eastern Diet - A Healthful Dietary Pattern from Eastern China: Its Characteristics and Relation to Adiposity, Cardiometabolic Diseases, Mortality and Gut Microbiota

Eastern Diet - A Healthful Dietary Pattern from Eastern China: Its Characteristics and Relation to Adiposity, Cardiometabolic Diseases, Mortality and Gut Microbiota

Cross‐sectional and longitudinal associations between body flexibility and sarcopenia

Physiotherapy Management combined with Blood Flow Restriction: A single case study

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