Crohn’s disease presenting as palatal ulcer

Abstract

Crohn's disease (CD) in children younger than 5 years of age is termed as early onset inflammatory bowel disease (EO-IBD). We report a 4 yr 6 mo-old child with EO-IBD, who presented with palatal ulcer, an extra intestinal manifestation of Crohn's disease as the dominant feature.

Crohn's disease should be considered in children with inflammatory oral lesions

“…The 28 original papers included in the review comprised nine observational studies, five retrospective studies and 14 case reports – five case series and nine single cases . We evaluated oral manifestations in patients with Crohn's disease at the ages of 2–19.7 years (mean age 11.6 ± 3.1 years) . We found that oral lesions were common in Crohn's disease and more prevalent in children.…”

“…1). The 28 original papers included in the review comprised nine observational studies, five retrospective studies and 14 case reportsfive case series and nine single cases (11)(12)(13)(14).…”

“…We evaluated oral manifestations in patients with Crohn's disease at the ages of 2-19.7 years (mean age 11.6 AE 3.1 years) (11)(12)(13)(14). We found that oral lesions were common in Crohn's disease and more prevalent in children.…”

“…Crohn's disease is a chronic transmural granulomatous inflammatory disorder, a type of inflammatory bowel disease (IBD) that may occur in any part of the gastrointestinal tract, including the mouth. The incidence of the childhood-onset disease is estimated to be 0.1-11.2 cases per 100 000 individuals per year, and an aetiopathogenesis role of immunological, genetic, infectious, environmental, psychosocial, dietary factors has been suggested (1,(3)(4)(5)(6)(7)(8)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). The prevalence of oral manifestations in adults is 0.5-20% (20,21).…”

Severe Refractory Orofacial Crohn’s Disease: Report of a Case

“…One case of facial and ileocolonic CD showed improvement of disease with total enteral nutrition [16]. Several case reports document remission of oral symptoms with topical or systemic steroids used in conjunction with aminosalicylates or mercaptopurine [4,17,18]. There have also been several cases of orofacial CD refractory to steroids which were treated successfully with IFX [7-9, 13, 19-22].…”