Crohn's disease of the mouth

Oral manifestations of Crohn's disease.

“…The age range, sex distribution, and site of disease in Crohn's patients with oral lesions were similar to those reported in the literature (Dudeney and Todd, 1969;Issa, 1971;Schiller et al, 1971;Bishop et al, 1972;Bottomley, Giorgini, and Julienne, 1972;Stankler et al, 1972;Varley, 1972;Eisenbud, Katzka, and Platt, 1972) and to those in the total sample of Crohn's patients examined, suggesting that these factors were unimportant in influencing the incidence of mouth lesions.…”

Oral signs and symptoms in relation to disease activity and site of involvement in patients with inflammatory bowel disease

“…This may be attributed to the small numbers. Previous studies demonstrated an increased prevalence of various oral symptoms in patients with IBD (Schiller et al, 1971;Valery, 1972;O'Loughlin and Perry, 1978;Basu and Asquith, 1980;Rooney, 1984;Sundh and Hulten, 1984;Frankel and Mostofi, 1985;Sundh and Emilson, 1989;Alstead et al, 1991;Chan et al, 1991;Weiss et al, 1991;Philpot et al, 1992;Seo et al, 1992;Storwick et al, 1994;Calobrisi et al, 1995;Lisciandrano et al, 1996). A direct correlation between disease activity and the prevalence of other oral lesions was found by most (Basu et al, 1975;Basu and Asquith, 1980;Halme et al, 1993;Veloso et al, 1996) but not all (Lisciandrano et al, 1996) previous studies, and was attributed to an altered immune response after an exacerbation of CD.…”

Oro-Facial Granulomatosis: Crohnʼs Disease or a New Inflammatory Bowel Disease?

“…The association of oral lesions with CD has been well described. This includes granulomatous inflammation affecting various sites in the oral cavity but also aphthous ulceration, gingivitis, angular cheilitis, glossitis, candidiasis, and dental caries 13‐15. Many of these features such as aphthous ulcers and glossitis are considered secondary to the effects of active inflammation elsewhere or to hematinic deficiency 5,6.…”