Crohn disease: state of the art.

Wills, John S.; Lobis, Ira F.; Denstman, Frederick

doi:10.1148/radiology.202.3.9051003

Cited by 117 publications

(69 citation statements)

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“…However, the detection of small erosions or aphthae by SBFT is beyond its capabilities [9]. For detecting early mucosal lesions, small bowel enteroclysis is more accurate than SBFT [10]. However, these barium studies are limited in observing the bowel wall, extraluminal extension and overlapping bowel loops.…”

Section: New Modalities For CDmentioning

confidence: 99%

Advancing Magnetic Resonance Imaging in Crohn's Disease

Fujii¹,

Kitazume

Saito³

et al. 2014

Digestion

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Crohn's disease (CD) is a lifelong chronic inflammatory bowel disease associated with diarrhea, abdominal pain, bloody stool and often perianal fistulae. Inflammation in CD involves the entire gastrointestinal tract, especially including the small and large bowels, causing irreversible bowel damage. Frequent imaging examinations are necessary to monitor disease activity and to evaluate response to therapeutic interventions, and, furthermore, to predict recurrence in order to provide appropriate treatment. The suitable imaging modality should be reproducible, well tolerated, safe and free of ionizing radiation. In recent years, imaging used in CD has dramatically changed. Cross-sectional imaging techniques such as computed tomography and magnetic resonance imaging (MRI) are used to investigate not only extraluminal abnormalities, but also intraluminal changes. Recently, new techniques such as MR enteroclysis, enterography, colonography and enterocolonography have been developed. These recent advances enable the use of MRI to assess bowel disorders with high sensitivity, specificity and accuracy. MRI can evaluate simultaneously the bowel surface, bowel wall, abdominal abscesses and perianal lesions, such as perianal fistulae and perianal abscesses, without the problem of overlapping bowel loops. Therefore, MRI has the potential for evaluation of the overall disease activity of CD without radiation exposure. We believe that MRI is a suitable first choice imaging modality in the assessment of CD.

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Section: New Modalities For CDmentioning

confidence: 99%

Advancing Magnetic Resonance Imaging in Crohn's Disease

Fujii¹,

Kitazume

Saito³

et al. 2014

Digestion

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“…[8][9][10] Başka bir çalışmada ise; BDK ile CH aktivitesi göstergesi olan ESR ve CRP tetkikleri arasında doğru orantı olduğu görülmüştür.…”

Section: Discussionunclassified

The Diagnostic Significance of Bowel Wall Thickening for Inflammatory Bowel Disease

Akbulut¹,

Sağ²,

Çakır³

2016

Turkiye Klinikleri J Pediatr

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“…7,8 However, some studies have demonstrated that SBFT is not accurate for detection of active CD in the small bowel. 9,10 It has been suggested that small bowel enteroclysis is more accurate than SBFT at detecting early mucosal lesions, 11,12 but both methods provide only limited and indirect information with regard to the state of the bowel wall and extraluminal extension of CD. Moreover, the effectiveness of these methods may be limited by overlapping bowel loops.…”

Section: Imaging Modalities In CDmentioning

confidence: 99%

Guide to magnetic resonance in Crohnʼs disease

Mazziotti

Ascenti

Scribano

et al. 2011

Inflammatory Bowel Diseases

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Considering that multiple imaging examinations are often necessary for monitoring Crohn's disease (CD) activity and severity in order to guide and monitor appropriate treatment, the ideal imaging test would be reproducible, well tolerated by patients, and free of ionizing radiation. For these reasons recent studies have highlighted the role of a magnetic resonance imaging (MRI) technique optimized for small bowel imaging in the evaluation of small bowel disorders. In this regard there are two main methodological approaches represented by MR enterography, following administration of an oral contrast medium, and MR enteroclysis, following administration of contrast medium through a nasojejuneal tube. MRI may be used to demonstrate the pathologic findings and complications of CD. In particular, MR has excellent sensitivity and specificity, ranging from 88%-98% and 78%-100%, respectively, for the detection of active inflammation, wall thickening, ulcerations, increased wall enhancement, increased vascularity, perienteric inflammation, and reactive adenopathy. MR also allows more accurate identification of associated complications including penetrating and fibrostenotic disease as well as the more rare extraintestinal manifestations that are usually associated with severe and longstanding intestinal inflammation, the latter often guiding the therapeutic approach. In the progression of CD some rare complications can occur that, to our knowledge, were only briefly or never mentioned in the radiological literature regarding MR enterography or enteroclysis and in which the application of these techniques play a key role.

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Crohn disease: state of the art.

Cited by 117 publications

References 0 publications

Advancing Magnetic Resonance Imaging in Crohn's Disease

Advancing Magnetic Resonance Imaging in Crohn's Disease

The Diagnostic Significance of Bowel Wall Thickening for Inflammatory Bowel Disease

Guide to magnetic resonance in Crohnʼs disease

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