Crimean-Congo hemorrhagic fever treated with ribavirin in a pregnant woman

Dizbay, Murat; Aktaş, Firdevs; Gaygısız, Ümmügülsüm; Özger, Hasan Selçuk; Özdemir, Kevser

doi:10.1016/j.jinf.2009.08.004

Cited by 12 publications

(12 citation statements)

References 14 publications

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“…The authors pointed out that she was already ill during pregnancy and this caused fetal mortality. In contrast, Dizbay et al [8] reported a pregnant woman infected with CCHF virus at term. A healthy baby was born by normal vaginal delivery and did not develop any symptoms compatible with CCHF infection; laboratory findings and both RT-PCR and ELISA IgM for CCHF virus of the baby revealed negative results.…”

Section: Discussionmentioning

confidence: 99%

“…In total, 8 published articles including case reports or case series and 1 poster presentation including 1 case could be accessed [3,8,9,10,11,12,13,14,15]. …”

Section: Case Series and Review Of The Literaturementioning

confidence: 99%

“…The clinical features of CCHF infection are well known. However, its course during pregnancy and the maternal and fetal outcomes are not entirely known because CCHF infections have been rarely reported during pregnancy [8,9]. To assess the impact of CCHF infection during pregnancy on maternal and fetal outcomes, we present the clinical and laboratory findings of 5 pregnant women with CCHF infection and the outcomes of their babies.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Favorable Outcomes for both Mother and Baby Are Possible in Pregnant Women with Crimean-Congo Hemorrhagic Fever Disease: A Case Series and Literature Review

Gözel

Elaldı

Engin

et al. 2014

Gynecol Obstet Invest

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To assess the impact of Crimean-Congo hemorrhagic fever (CCHF) infection during pregnancy on maternal and fetal outcomes, we present the clinical and laboratory findings and outcomes of 5 pregnant women with CCHF infection as well as fetal outcomes. We also reviewed previously reported cases with CCHF infection in pregnant women. All pregnant women with CCHF infection who had been hospitalized between August 2007 and September 2011 were included. The gestational ages at the time of CCHF infection were 8, 18, 20, 21 and 32 weeks. CCHF infection was acquired during the 1st trimester in only 1 case and resulted in spontaneous abortion. The other 4 pregnant women completely recovered, all reached a healthy full-term gestation and 4 term babies were born. All infants had normal birth weight and were found to be healthy on their first examination and follow-up. In the literature concerning CCHF infection in pregnancy, 8 published articles including case reports or case series and 1 poster presentation including 1 case could be accessed. In conclusion, there is a risk of vertical transmission of CCHF infection, and infections acquired early in gestation had a poor prognosis for the fetus.

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Section: Discussionmentioning

confidence: 99%

“…In total, 8 published articles including case reports or case series and 1 poster presentation including 1 case could be accessed [3,8,9,10,11,12,13,14,15]. …”

Section: Case Series and Review Of The Literaturementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Favorable Outcomes for both Mother and Baby Are Possible in Pregnant Women with Crimean-Congo Hemorrhagic Fever Disease: A Case Series and Literature Review

Gözel

Elaldı

Engin

et al. 2014

Gynecol Obstet Invest

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“…Ribavirin kullanımı gebelikte kontrindikedir (FDA gebelik kategorisi X); ama annenin yaşamının kurtarılması icin gerekli olabilir. Kanıtlanmış KKKA tanısı alan bir gebede ribavirin kullanılmış, anne ölmemiş ve sağlıklı olarak bebeğini doğur-muştur (46).…”

Section: Gebelikte Ribavirin Kullanımıunclassified

Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin

Ergönül¹

2016

Klimik Dergisi

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“…They also reported that the patient's recovery and good health of the fetus might be related to ribavirin treatment. 6 In this present study, ribavirin was not given to the two pregnant patients, but the patients recovered by only using the symptomatic treatment. Horizontal transmission of the disease from mother to the fetus was shown.…”

Section: Discussionmentioning

confidence: 81%

Crimean-Congo hemorrhagic fever and pregnancy: Two cases

Duygu¹,

Çiçek²,

Turan³

2015

Journal of Microbiology and Infectious Diseases

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Crimean-Congo Hemorrhagic Fever (CCHF) is a viral zoonosis, transmitted to humans by either: the Hyalomma species of ticks; or by direct contact with body fluids or tissues of infected humans or domestic animals. CCHF can result in death through clinical progression of hemorrhagic fever (1). Tokat Province in Turkey is where CCHF cases are seen at the highest rate.In this article, the cases of two pregnant women are discussed. The women applied in Tokat with a fever and were diagnosed with CCHF. Along with symptomatic treatment, thrombocyte and fresh frozen plasma replacement was performed in one of the patient's cases. Patients were discharged with recovery. The main purpose of this article is to enlighten the progression of CCHF during pregnancy. J Microbiol Infect Dis 2015;5(1): 29-31

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Crimean-Congo hemorrhagic fever treated with ribavirin in a pregnant woman

Cited by 12 publications

References 14 publications

Favorable Outcomes for both Mother and Baby Are Possible in Pregnant Women with Crimean-Congo Hemorrhagic Fever Disease: A Case Series and Literature Review

Favorable Outcomes for both Mother and Baby Are Possible in Pregnant Women with Crimean-Congo Hemorrhagic Fever Disease: A Case Series and Literature Review

Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin

Crimean-Congo hemorrhagic fever and pregnancy: Two cases

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