1973
DOI: 10.1093/oxfordjournals.aje.a121567
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Creutzfeldt-Jakob Disease: A Case-Control Study

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Cited by 77 publications
(31 citation statements)
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“…How prions causing disease arise in patients with sporadic forms is unknown; hypotheses include horizontal transmission of prions from humans or animals (242), somatic mutation of the PrP gene, and spontaneous conversion of PrP C into PrP Sc (5,15). Because numerous attempts to establish an infectious link between sporadic CJD and a preexisting prion disease in animals or humans have been unrewarding, it seems unlikely that transmission features in the pathogenesis of sporadic prion disease (9)(10)(11)(12)243).…”
mentioning
confidence: 99%
“…How prions causing disease arise in patients with sporadic forms is unknown; hypotheses include horizontal transmission of prions from humans or animals (242), somatic mutation of the PrP gene, and spontaneous conversion of PrP C into PrP Sc (5,15). Because numerous attempts to establish an infectious link between sporadic CJD and a preexisting prion disease in animals or humans have been unrewarding, it seems unlikely that transmission features in the pathogenesis of sporadic prion disease (9)(10)(11)(12)243).…”
mentioning
confidence: 99%
“…The duration of the human illness varies from patient to patient (22), some lasting one to several months (type I), others less than 9 months (type II), and still others lasting as long as 1-2 years (type III). The present investigation in hamsters strongly suggests that some of these Creutzfeldt-Jakob subgroups, displaying different syndromes and different durations of human disease, may be related to the action of different strains of the Creutzfeldt-Jakob agent.…”
Section: Resultsmentioning
confidence: 99%
“…Einen Überblick über die bisherigen Studien geben die Tabellen 15 und 16. Die Studienergebnisse von Bobowick et al (1973), Kondo und Kuroiwa (1982), Davanipour et al (1985), Harries-Jones et al (1988) (Poser et al 1999, Heinemann et al 2007a (Davanipour et al 1985). …”
Section: Anzahlen Von Operationen Und Bluttransfusionenunclassified