“…Despite disadvantages, such as the necessity of a secondary procedure, distraction osteogenesis has several advantages: the operation is simple, the operation time is short, the bleeding and transfusions are less, there is decreased incidence of infections, epidural dead space formation is avoided, and the tension of the skin and subcutaneous soft tissues is decreased [3,4,5,6,7,8]. However, all procedures to date have still been complicated, taken a long period of time, and shown a marked loss of blood (and hence increased volume of transfusions), and a greater overall risk in infants and young children [1,9,10]. The mean operation times for classical craniotomy/remodeling and distraction osteogenesis have been reported to range from 150 to 441 and from 183 to 336 min, respectively, and the mean volume of transfused blood ranged from 100 to 426 and 178 to 350 ml, respectively, indicating a high risk for children undergoing classical craniotomy and remodeling [3,4,6,9,11,12].…”