1985
DOI: 10.3171/jns.1985.62.1.0132
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Craniopharyngioma with erosion and drainage into the nasopharynx

Abstract: This physician had a craniopharyngioma which was treated by radiation therapy in 1938, with relief of headaches and return to professional activity. Later, penetration of the tumor through the sphenoid sinus into the nasopharynx resulted in the intermittent drainage over 30 years of cystic parts of the tumor into the nasopharynx and from there to the oropharynx without any meningeal rupture. Radiation therapy was the initial mode of treatment, later combined with steroid and thyroid replacement therapy. A prof… Show more

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Cited by 30 publications
(17 citation statements)
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“…Such craniopharyngioma may have completely different presentation from typical endocrinopathy and visual deficit and instead it may present with conglomeration of variable symptoms, which depends on extent of involvement and obstruction of ostia of the paranasal sinuses causing difficulty in breathing, nasal obstruction and sinus headache. These craniopharyngioma with sellar component can also encroach and the sella floor and cause direct compression of pituitary gland or secondary to vascular compromise leads endocrinopathy [10][11][12][13][14][15][16][17]19,21,25,27,28,32]. So, majority of infrasellar reported craniopharyngioma usually had an intrasellar extension.…”
Section: Discussionmentioning
confidence: 99%
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“…Such craniopharyngioma may have completely different presentation from typical endocrinopathy and visual deficit and instead it may present with conglomeration of variable symptoms, which depends on extent of involvement and obstruction of ostia of the paranasal sinuses causing difficulty in breathing, nasal obstruction and sinus headache. These craniopharyngioma with sellar component can also encroach and the sella floor and cause direct compression of pituitary gland or secondary to vascular compromise leads endocrinopathy [10][11][12][13][14][15][16][17]19,21,25,27,28,32]. So, majority of infrasellar reported craniopharyngioma usually had an intrasellar extension.…”
Section: Discussionmentioning
confidence: 99%
“…The anterior wall of Rathke's pouch forms both the pars tuberalis and pars distalis of anterior lobe of pituitary, being regarded as the commonest site of origin of craniopharyngioma and rarely also occur along the carniopharyngeal duct which extends from the pharynx up to the floor of sella [2][3][4]. Craniopharyngioma is mostly located usually above the sella floor but extension into sinus is very rare and with unusual [5][6][7][8][9][10][11][12][13][14][15][16][17]. About eleven cases of infrasellar craniopharyngioma are reported in the literature, whose either majority of the chief epicenter or wholly tumour is located in the infrasellar region.…”
Section: Introductionmentioning
confidence: 99%
“…The signs of pituitary dysfunction appear early in the cases in which the tumor expands within the sella. The tumor located at the sphenoid sinus usually presents with headache and cavernous sinus syndrome [6][7][8]11,12,15,17,20,23,24,27 . The craniopharyngiomas located in the nasopharyngeal region usually present with frontal headache, nasal obstruction, epistaxis, nasopharyngeal and/or nasal fossa masses 3,5,9,10,13,15,18,19,22,25,26,29,32,34 .…”
Section: Discussionmentioning
confidence: 99%
“…Multiple calcifications are observed within the tumor, especially in younger patients. In adults, craniopharyngiomas are often not calcified 17,19,[21][22][23]26,27,29,30,32,35,40 . Magnetic resonance image clearly showed the tumor extension, cystic portions, mixed intensity signal, inhomogeneous or heterogeneous enhancement 17,23,[25][26][27][28][29][30]32,34,40 .…”
Section: Discussionmentioning
confidence: 99%
“…To our knowledge, 40 craniopharyngiomas involving the infrasellar region have been reported to date in 23 male and 17 female patients with a median age of 25 years (range 0–71 years) [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]. The peak incidence is in the 21- to 30-year-old group, which is higher than that of the series of Yaşargil [43](6–10 years old).…”
Section: Discussionmentioning
confidence: 99%