Craniofacial Resection for Cranial Base Malignancies Involving the Infratemporal Fossa

Bilsky, Mark H.; Bentz, Brandon G.; Vitaz, Todd W.; Shah, Jatin P.; Kraus, Dennis H.

doi:10.1227/01.neu.0000176648.06547.15

Cited by 39 publications

(39 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The transfacial, transmaxillary, transoral-transantral, and transpalatal anterior open approaches were described [4]. The advantage of these approaches is avoidance of the temporomandibular joint and facial nerve; however, facial skeletal deformities could be significant and surgical viewing is not wide enough for all areas of the ITF.…”

Section: Discussionmentioning

confidence: 99%

“…We have used this approach in selected cases of extensive lesions with mastication muscle involvement and trismus. The external approaches for the ITF remain a procedure of choice in the case of malignant or extensive benign lesions [4]. In our experience, the described approach may be indicated in cases with extensive malignant lesions to improve the quality of life and to reduce the pain even in patients with an extremely high risk of recurrent disease or in cases when chemoradiation is not possible.…”

Section: Discussionmentioning

confidence: 99%

“…There is a wide description of a variety of surgical procedures with external or endoscopic endonasal approaches for removal of extracranial lesions at the skull base [2,3,4,5,6]. Inadequate exposure and high local morbidities (facial nerve function, middle ear, etc.)…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Preauricular Transmandibular and Transzygomatic Approach for Tumors of the Infratemporal Fossa Revisited

Timoshenko

Asanau²,

Gavid³

et al. 2013

ORL

View full text Add to dashboard Cite

Aim: To demonstrate the surgical technique and results in patients operated on with a preauricular transmandibular transzygomatic approach. Methods: This surgical technique was used in 21 patients with benign and malignant tumors of the infratemporal fossa (ITF), operated on between 1999 and 2011. Results: Twenty-one patients were enrolled in the study. There were 6 patients with benign tumors and 15 with malignant ones. No patients with benign lesions show any disease recurrence 5 years after surgery and present excellent functional and cosmetic results. Postoperatively, a reduction of pain was noted in all patients with malignant lesions. Four patients in this group, who are alive 5 years after surgery, do not demonstrate any disease progression. Conclusion: The described approach provides an excellent exposure of the ITF and could be the procedure of choice in the management of ITF tumors.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Preauricular Transmandibular and Transzygomatic Approach for Tumors of the Infratemporal Fossa Revisited

Timoshenko

Asanau²,

Gavid³

et al. 2013

ORL

View full text Add to dashboard Cite

show abstract

“…Бåðóчè äî óâàãè «îíêîëîã³чíó íåðåзåêö³éí³ñòü ïóхëèí», âàae-ëèâèм мîмåíòîм є ïðîãíîñòèчí³ чèííèêè яê зàñ³б îбãðóíòóâàííя ïîêàзàíü äî âèêîíàííя îïåðàö³¿ òà òàêòèêè ïîäàëüшîãî ë³êóâàííя хâîðîãî, ï³äâèщåííя ïîêàзíèê³â зàãàëüíîãî âèaeèâàííя îïåðîâàíèх хâî-ðèх. Ç òàêèх ïðîãíîñòèчíèх чèííèê³â ð³зí³ àâòîðè âèä³ëяюòü ã³ñòîëîã³ю ïóхëèí, «чèñòèé êðàé» ï³ñëя âèäàëåííя ïóхëèíè, ïðîðîñòàííя ТÎÃМ, ³íâàз³ю òêàíèíè мîзêó, ïîшèðåííя ïóхëèíè ³íòðàîðб³òàëü-íî чè íà ïåчåðèñòèé ñèíóñ [6,7,13]. Мè ïðîïîíóємî âêëючèòè äîäàòêîâèé чèííèê -òðèâàë³ñòü зàхâî-ðюâàííя.…”

Section: кëючîâ³ ñëîâà: пухлини основи черепа злоякісні пухлини хірunclassified

Skull base malignancies. Surgical perspectives

Palamar¹,

Huk²

2008

Ukr Neurosurg J

View full text Add to dashboard Cite

“…3,4,27,43,45 Standard therapy for this malignancy has most commonly included a strategy of local resection followed by adjuvant radiation therapy. 6,13,16,17,23,24,28,30,35,38,39,43,46,47,52 Chemotherapy using agents such as carboplatinum and paclitaxel has been used, but with limited results. 2,11,12,15,26,27,36,41,44,[48][49][50] ACC can arise in any salivary gland, both major and minor.…”

mentioning

confidence: 99%

Adenoid cystic carcinoma of the skull base: results with an aggressive multidisciplinary approach

Ramakrishna¹,

Raza²,

Kupferman

et al. 2016

JNS

View full text Add to dashboard Cite

A denoid cystic carcinoma (ACC) is a locally aggressive salivary gland malignancy prone to perineural invasion and metastasis. Local recurrences often involve the skull base, whereas distant metastases most frequently involve the lung, bones, and liver. 3,4,27,43,45 Standard therapy for this malignancy has most commonly included a strategy of local resection followed by adjuvant radiation therapy. 6,13,16,17,23,24,28,30,35,38,39,43,46,47,52 Chemotherapy using agents such as carboplatinum and paclitaxel has been used, but with limited results. 2,11,12,15,26,27,36,41,44,[48][49][50] ACC can arise in any salivary gland, both major and minor. Consequently, these tumors can be located in the tongue, trachea, palate, larynx, and paranasal sinuses. 27Tumors in the sinonasal cavity can remain undetected for long periods of time with minimal symptoms. Only after sufficient soft-tissue involvement, bone destruction, or cranial nerve involvement does the malignancy become manifest. Therefore, a strategy of maximal resection with minimal morbidity often presents a substantial therapeutic challenge given the complex anatomy of lesions that involve the paranasal sinuses and extend intracranially into the anterior or middle fossa.abbreviatioNs ACC = adenoid cystic carcinoma; EGFR = epidermal growth factor receptor; ICA = internal carotid artery; OS = overall survival; PFS = progression-free survival; VEGF = vascular endothelial growth factor. submitted October 28, 2014. accepted January 5, 2015. iNclude wheN citiNg Published online August 7, 2015; DOI: 10.3171/2015.1.JNS142462. disclosure The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper. results Median follow-up for study patients was 6.75 years. The 5- and 10-year overall survival (OS) rates were 78% and 50%, respectively. Sixty-six percent of patients had progression of their disease. The 5- and 10-year progressionfree survival (PFS) rates were 46.7% and 21.0%, respectively. Gross-total resection was achieved in 75% of patients, with 49% having microscopically negative margins at the time of first operation. On univariate analysis, resections with microscopically negative margins were associated with a significant OS advantage (20.1 ± 3.3 years) compared with resections that left residual disease, even if microscopic (10.3 ± 1.6 years, p = 0.035). In patients who underwent reoperation, the effect persisted, with improved OS in those with negative margins (21.4 ± 0.0 vs 16.7 ± 4.0 years, p = 0.06). The use of adjuvant radiotherapy was associated with an OS advantage (16.2 ± 2.5 vs 5.5 ± 2.2 years, p = 0.03) at initial diagnosis and improved PFS (7.8 ± 1.0 vs 2.1 ± 0.62 years, p = 0.005), whereas repeat irradiation provided no benefit. The use of adjuvant chemotherapy at diagnosis or at recurrence was not associated with any significant advantage. Multivariate analysis revealed margin-negative resection at initial operation and at recurrence retained OS significance, even after controlling...

show abstract

Craniofacial Resection for Cranial Base Malignancies Involving the Infratemporal Fossa

Cited by 39 publications

References 16 publications

Preauricular Transmandibular and Transzygomatic Approach for Tumors of the Infratemporal Fossa Revisited

Preauricular Transmandibular and Transzygomatic Approach for Tumors of the Infratemporal Fossa Revisited

Skull base malignancies. Surgical perspectives

Adenoid cystic carcinoma of the skull base: results with an aggressive multidisciplinary approach

Contact Info

Product

Resources

About