1997
DOI: 10.3109/02841859709172059
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Cranial MR findings in Wilson's disease

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Cited by 11 publications
(8 citation statements)
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“…The commonest MRI brain changes included symmetrical high T2 signal in both putamena with a concentric-laminar pattern [8,9]. Hyperintense T2 signal in glopi pallidi, brainstem, both thalami, cerebellum were observed in many cases [10,11,12].…”
Section: Discussionmentioning
confidence: 99%
“…The commonest MRI brain changes included symmetrical high T2 signal in both putamena with a concentric-laminar pattern [8,9]. Hyperintense T2 signal in glopi pallidi, brainstem, both thalami, cerebellum were observed in many cases [10,11,12].…”
Section: Discussionmentioning
confidence: 99%
“…T2 high signal intensity in the putamen is the most common MRI finding [4]. This is because the copper concentration is the highest and astrocytic reaction is prominent in the putamen in Wilson disease, while under physiological conditions, concentrations of copper can be found in the locus.…”
Section: Discussionmentioning
confidence: 99%
“…Copper deposition (seen as hyperintensities on T2weighted scans) in the putamen and globus pallidus, liver, and cornea are characteristic of WilsonÕs disease [42,43], as is the so-called Ôface of the giant pandaÕ sign (referring to the combination of high signal intensity in the tegmentum except for the red nucleus with preservation of signal intensity of the lateral portion of the pars reticulata of the substantia nigra and hypointensity of the superior colliculus) [44].…”
Section: Clues From Neuroimagingmentioning
confidence: 99%