Magnetic Resonance Imaging of Brain in Patient with Late-Onset Wilson’s Disease: A Case Report and Review of Literature

Abstract

Wilson's disease is a worldwide inherent gene disorder leads to copper deposition in various tissues.Recently, wilson's disease is classified according to onset of symptoms into early-onset and late-onset wilson. Reported a 56-year-old male patient presenting with dysarthria and dyskinesia. Laboratory tests revealed elevated urinary cupper without elevation of liver function tests. Magnetic resonance imaging of the brain was performed and revealed typical bilateral putamena and midbrain tegmental T2 hyperintensity "Face of giant Panda" sign which are reliable imaging features of wilson's disease and the case represents a late-onset type. Medical treatment was prescribed for the patient with regular follow up.