CPSE determination and detection of canine prostatic diseases: The importance of a specific diagnosis

Comparative Evaluation of Diagnostic Methods for Subclinical Benign Prostatic Hyperplasia in Intact Breeding Male Dogs

“…It is imperative to acknowledge that previous investigations have predominantly relied on Enzyme-Linked Immunosorbent Assay (ELISA) tests for the analysis of CPSE values [12,24,26]. In contrast, our study adopted a laser-induced fluorescence immunochromatographic analyzer, a method we deemed more reliable than ELISA.…”

“…A comprehensive diagnostic approach includes a full patient history, rectal palpation, evaluation of the organ using diagnostic imaging tools, semen collection, and culture and cytology of prostate tissue or fluid samples. Moreover, the levels of a distinct biomarker for prostatic disease, canine prostate-specific esterase (CPSE), is now highly recommended [12].…”

Diagnostic tests in canine andrology - What do they really tell us about fertility?

“…For the examination of the prostate, ultrasound is considered an excellent tool to detect any change of their homogeneous and echogenicity pattern of the gland. These features, however, are not pathognomonic of a specific disease [37,38]. For instance, the loss of normal ultrasonographic pattern and the increase in echogenicity can be observed in almost every prostatic disorder [39].…”

“…Therefore, a sexual rest of at least 24 h before sampling has been recommended [48]. Since, an accurate diagnosis of prostatic diseases is crucial and challenging because a variety of different disorders share the same clinical signs, several diagnostic tools need to be used [37]. Measurement of concentrations of FSH and LH in blood serum or plasma provides good insights into the hormonal regulation [49] but not all laboratories provide reliable quantitative tests for these parameters, yet.…”