Coxiella burnetii-positive PCR in febrile patients in rural and urban Africa

Abstract

The installation of point-of-care laboratories in rural Africa can be a very effective tool for studying the epidemiology of many infectious diseases.

Molecular Detection of Fastidious and Common Bacteria as Well as Plasmodium spp. in Febrile and Afebrile Children in Franceville, Gabon

“…8 Recent studies performed in western sub-Saharan Africa have shown the role of emergent and fastidious bacteria, such as Rickettsia felis, Coxiella burnetii, Tropheryma whipplei, Borrelia crocidurae, and Bartonella spp., as the cause of fever. [9][10][11][12][13][14][15] Rickettsia felis and Borrelia duttonii were also found in eastern Africa. [16][17][18] Some of them had already been described in Gabon.…”

First genetic evidence of Coxiella burnetii in cases presenting with acute febrile illness, India

“…Proper patient management can significantly reduce mortality due to chronic Q fever, making timely diagnosis of utmost importance. Although C. burnetii causing acute febrile illness has been reported worldwide [5,6], its distribution in India is ill-defined.…”

Co-circulation of Plasmodium and Bacterial DNAs in Blood of Febrile and Afebrile Children from Urban and Rural Areas in Gabon

“…However, some, such as C. burnetii, Bartonella spp., and T. whipplei, remain limited to a few countries such as Senegal. 33,34 This restriction in the distribution of these fastidious bacteria is explained by the lack of studies in other African countries. Most interestingly, we here report bacteremia related to T. whipplei in Gabon for the first time.…”

“…Indeed, the use of afebrile subjects as the control group during studies on fever in Africa is significant. [18][19][20][21]34 It shows that microorganisms previously considered pathogens can easily be found in healthy persons. 32 Unfortunately, most of the fever studies previously conducted in Africa failed to use control groups.…”