Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

Pontes, Mariana; Ribeiro, Tereza Cristina Medrado; Ribeiro, Hugo; Mattos, Ângela Peixoto de; Almeida, Indhira; Leal, Vanessa Maranhão Alves; Cabral, Gabriela; Stolz, Suzanne; Zhuang, Weihong; Scalabrin, Deolinda

doi:10.1186/s12937-016-0138-0

Cited by 18 publications

(16 citation statements)

References 61 publications

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“…Positive effects of the administration of prebiotics has been shown by Ziegler et al, who investigated the administration of a GOS and PDX mix and found a statistical difference in the occurrence of eczema (prebiotics vs. control: 18 vs. 7%) [47]. The same combination was used by Pontes et al in their study, who reported a lower number of allergic diseases including AD in the analyzed group receiving prebiotics [53]. Three trials investigating the relationship between GOS supplementation and preventing eczema shown a decreased risk of developing AD [46,48,49].…”

Section: Atopic Dermatitismentioning

confidence: 66%

Microbiome Modulation as a Therapeutic Approach in Chronic Skin Diseases

et al. 2021

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There is a growing quantity of evidence on how skin and gut microbiome composition impacts the course of various dermatological diseases. The strategies involving the modulation of bacterial composition are increasingly in the focus of research attention. The aim of the present review was to analyze the literature available in PubMed (MEDLINE) and EMBASE databases on the topic of microbiome modulation in skin diseases. The effects and possible mechanisms of action of probiotics, prebiotics and synbiotics in dermatological conditions including atopic dermatitis (AD), psoriasis, chronic ulcers, seborrheic dermatitis, burns and acne were analyzed. Due to the very limited number of studies available regarding the topic of microbiome modulation in all skin diseases except for AD, the authors decided to also include case reports and original studies concerning oral administration and topical application of the pro-, pre- and synbiotics in the final analysis. The evaluated studies mostly reported significant health benefits to the patients or show promising results in animal or ex vivo studies. However, due to a limited amount of research and unambiguous results, the topic of microbiome modulation as a therapeutic approach in skin diseases still warrants further investigation.

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Section: Atopic Dermatitismentioning

confidence: 66%

Microbiome Modulation as a Therapeutic Approach in Chronic Skin Diseases

et al. 2021

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“…However, whether supplementing breast milk-derived prebiotics prevents AD is still questionable. Supplementing HMOs, mostly galacto-oligosaccharide (GOS) and fructo-oligosaccharide (FOS), effectively reduced the incidence of AD during infancy but exhibited poor long-term protection in several RCTs [257][258][259][260][261][262][263][264]. The results from other trials were not sufficiently in favour of supplementing HMOs in treating AD [265][266][267][268][269][270][271].…”

Section: Prebiotics In Preventing and Treating Admentioning

confidence: 99%

Manipulating Microbiota to Treat Atopic Dermatitis: Functions and Therapies

et al. 2022

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Atopic dermatitis (AD) is a globally prevalent skin inflammation with a particular impact on children. Current therapies for AD are challenged by the limited armamentarium and the high heterogeneity of the disease. A novel promising therapeutic target for AD is the microbiota. Numerous studies have highlighted the involvement of the skin and gut microbiota in the pathogenesis of AD. The resident microbiota at these two epithelial tissues can modulate skin barrier functions and host immune responses, thus regulating AD progression. For example, the pathogenic roles of Staphylococcus aureus in the skin are well-established, making this bacterium an attractive target for AD treatment. Targeting the gut microbiota is another therapeutic strategy for AD. Multiple oral supplements with prebiotics, probiotics, postbiotics, and synbiotics have demonstrated promising efficacy in both AD prevention and treatment. In this review, we summarize the association of microbiota dysbiosis in both the skin and gut with AD, and the current knowledge of the functions of commensal microbiota in AD pathogenesis. Furthermore, we discuss the existing therapies in manipulating both the skin and gut commensal microbiota to prevent or treat AD. We also propose potential novel therapies based on the cutting-edge progress in this area.

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“…It was reported that consuming seafood during pregnancy did not increase AR prevalence ( 60 ). AR prevalence was higher in 1-4-year-olds that consumed cow milk three times a day ( 61 ). The effect of dietary habits on AR prevalence was investigated in children.…”

Section: Epidemiology Of Allergic Rhinitismentioning

confidence: 99%

Turkish Guidelines for Diagnosis and Treatment of Allergic Rhinitis (ART)

Ecevit¹,

Özcan²,

Can³

et al. 2021

TAO

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Object: To prepare a national guideline for Otorhinolaryngologist who treat allergic rhinitis patients. Methods: The study was conducted by three authors, namely the writing support team. The support team made the study plan, determined the writing instructions, chose the subgroups including the advisory committee, the advisors for authors and the authors. A workshop was organized at the very beginning to explain the details of the study to the team. Advisors took the chance to meet their coworkers in their subgroups and determined the main headings and subheadings of the guideline, together with the authors. After key words were determined by the authors, literature search was done in various databases. The authors keep in touch with the advisors and the advisors with the advisory committee and the support group at every stage of the study. National and International published articles as well as the abstracts of unpublished studies, imperatively presented in National Congresses, were included in this guideline. Only Guideline and meta-analyses published in last seven years (2013-2017) and randomized controlled studies published in last two years (2015-2017) were included. After all work was completed by the subgroups, support team brought all work together and edited the article. Results: A detailed guideline about all aspects of allergic rhinitis was created. Conclusion: The authors believe that this guideline will enable a compact and up-to-date information on allergic rhinitis to healthcare professionals. This guideline is the first in the field of Otolaryngology in Turkey. It should be updated at regular intervals.

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Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

Cited by 18 publications

References 61 publications

Microbiome Modulation as a Therapeutic Approach in Chronic Skin Diseases

Microbiome Modulation as a Therapeutic Approach in Chronic Skin Diseases

Manipulating Microbiota to Treat Atopic Dermatitis: Functions and Therapies

Turkish Guidelines for Diagnosis and Treatment of Allergic Rhinitis (ART)

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