COVID-19 vaccination in animals: A strategy for combating the global outbreak

Choudhary, Om Prakash; Choudhary, Priyanka; Saied, AbdulRahman A.

doi:10.1016/j.ijsu.2022.106848

Cited by 4 publications

(2 citation statements)

References 16 publications

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“…In fact, the list of animals susceptible to the virus is extensive and, besides apes and monkeys, includes pets, livestock and wildlife animals 41,42 . Because animals serve as natural reservoirs for viruses and viruses can even spread across species, vaccination of susceptible species is considered critical to prevent future re-emergence of the virus [43][44][45] . The available veterinary vaccines (Carnivac-Cov, Zoetis, Ancovax) have been primarily developed for, and tested on, dogs, cats, and minks 46,47 , although the Zoetis vaccine has been given to gorillas as well 43 .…”

Section: Discussionmentioning

confidence: 99%

Monitoring and immunogenicity of SARS-CoV-2 vaccination of laboratory rhesus monkeys (Macaca mulatta)

Grothe

Lukaß

et al. 2023

Sci Rep

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The availability of effective vaccines and a high vaccination rate allowed the recent mitigation, or even withdrawal, of many protective measures for containing the SARS CoV-2 pandemic. At the same time, new and highly mutated variants of the virus are found to have significantly higher transmissibility and reduced vaccine efficacy, thus causing high infection rates during the third year of the pandemic. The combination of reduced measures and increased infectivity poses a particular risk for unvaccinated individuals, including animals susceptible to the virus. Among the latter, non-human primates (NHPs) are particularly vulnerable. They serve as important models in various fields of biomedical research and because of their cognitive capabilities, they receive particular attention in animal welfare regulations around the world. Yet, although they played an extraordinarily important role for developing and testing vaccines against SARS-CoV-2, the protection of captive rhesus monkeys against Covid-19 has rarely been discussed. We here report upon twofold mRNA vaccination of a cohort of 19 elderly rhesus monkeys (Macaca mulatta) against infection by SARS-CoV-2. All animals were closely monitored on possible side effects of vaccination, and were tested for neutralising antibodies against the virus. The data show that vaccination of rhesus monkeys is a safe and reliable measure to protect these animals against SARS-CoV-2.

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Section: Discussionmentioning

confidence: 99%

Monitoring and immunogenicity of SARS-CoV-2 vaccination of laboratory rhesus monkeys (Macaca mulatta)

Grothe

Lukaß

et al. 2023

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Lions already face numerous threats, including habitat loss, poaching, and disease; introduction of a novel virus like SARS-CoV-2 could have devastating consequences for their populations ( 7 ). Therefore, strengthening biosecurity measures in wildlife conservation centers and promoting vaccination of susceptible animal species whenever feasible and safe are crucial for mitigating viral transmission and protecting vulnerable wildlife populations ( 1 , 9 ).…”

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confidence: 99%