COVID-19 Vaccination and Asymptomatic Infection

Pratò, Simone; Paladino, María Emilia; Riva, Michele Augusto; Belingheri, Michael

doi:10.1097/jom.0000000000002389

Cited by 10 publications

(4 citation statements)

References 8 publications

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“…The authors reported a rate of 1.6% after the first vaccine dose and 6.1% after the second [ 36 ]. Sick leave following vaccination is certainly an important aspect to consider, but it should be regarded in light of the fact that vaccination reduces HW sick leave due to infection and that it most likely reduces the duration of sick leave when infection occurs despite vaccination [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

Cumulative Incidence of SARS-CoV-2 in Healthcare Workers at a General Hospital in Germany during the Pandemic—A Longitudinal Analysis

Platten

Nienhaus

Peters

et al. 2022

IJERPH

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Health workers (HW) are at increased risk for SARS-CoV-2 infection. In order to monitor the infection dynamic on the basis of contact with patients, HW at the St. Antonius Hospital (SAH) were tested four times in one year by PCR and serology. The cumulative incidence of infection in HW was calculated. Swab and blood tests were simultaneously performed between April 2020 and April 2021. Risk factors and demographic information were assessed at the beginning of the study. The response rate was above 75% in all rounds of testing. The study comprised 1506 HW, 165 (10.6%) of which tested positive for SARS-CoV-2 infection. Working in an ICU or on wards with patient contact were risk factors (OR 4.4, 95% CI 1.73–13.6 and OR 2.9, 95% CI 1.27–8.49). At the end of the study, the majority of HW (810 of 1363 (59.4%)) had been vaccinated at least once. A total of 29.1% of unvaccinated HW and 5.3% of vaccinated HW showed an immune response typical for natural SARS-CoV-2 infection. Of the 73 HW who provided information on the course of the disease, 31.5% reported that their quality of life continued to be impaired. The cumulative incidence of infection was low in these HW, which may be attributed to vaccination and good hygiene. Nevertheless, a work-related infection risk was identified, highlighting the need to improve protection against infection. A high risk of developing long COVID was found after the infection has subsided. Special rehabilitation programs should be provided and HW should be compensated for reduced work capacity in the case that rehabilitation fails or takes a long time.

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Section: Discussionmentioning

confidence: 99%

Cumulative Incidence of SARS-CoV-2 in Healthcare Workers at a General Hospital in Germany during the Pandemic—A Longitudinal Analysis

Platten

Nienhaus

Peters

et al. 2022

IJERPH

View full text Add to dashboard Cite

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“…The sick leave period was longer, with a duration of about 35 days, but the study is not comparable to ours due to main differences in study population (general population, not only HCWs) and because those who contracted the infection received sickness benefit during the period from 1 March to 31 August 2020 [ 26 ]. A further study, in Northern Italy, focused on HCWs; in addition to a decrease in incidence following vaccination, the median sick leave period was 12 days for unvaccinated HCWs and 11 days for vaccinated HCWs [ 18 ]. Our study mainly focused on the evaluation of variations of sick leave period with chronological time; therefore, it was in correlation with vaccination times, COVID-19 variants, and changes in the bureaucratic management of cases.…”

Section: Discussionmentioning

confidence: 99%

“…Studies have shown that the pandemic has led to an increase in sick leave periods among the HCWs [ 15 , 16 ], that vaccinated HCWs have a reduced incidence and a shortened sick leave length than before vaccination [ 18 ], that return-to-work time for fully vaccinated HCWs was significantly shorter than that of partially vaccinated/unvaccinated HCWs, that fully vaccinated HCWs also showed milder symptom profiles compared to partially vaccinated and unvaccinated HCWs [ 19 ], and that sick leave utilization among HCWs declined significantly after vaccines became available [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Association between COVID-19 and Sick Leave for Healthcare Workers in a Large Academic Hospital in Southern Italy: An Observational Study

Palladino

Mercogliano

Fiorilla

et al. 2022

IJERPH

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Studies have shown that the pandemic has led to an increase in sick leave periods among healthcare workers (HCWs); however, this might have changed over time considering increase in vaccination coverage and change in COVID-19 variant predominance. Therefore, we conducted an observational study to evaluate whether the type of symptoms and the duration of sick leave period for healthcare workers working in a large university hospital in the South of Italy changed between January 2021 and January 2022; 398 cases of COVID-19 were identified for a total of 382 subjects involved. A total of 191 subjects answered the questionnaire about symptoms; of these, 79 had COVID-19 during the period from March 2020 until February 2022. The results showed a decrease of about 1.2 days in sick leave period for each quarter without finding significant differences in the perception of symptoms. It is possible to hypothesize a contribution from the Omicron variant to the decrease in sick leave period in the last quarter, from vaccination coverage, from optimization of COVID-19 management, and from change in the regulations for the assessment of positivity.

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“…Several studies 3,4 found that sick leave utilization among healthcare workers (HCW) declined significantly after vaccines became available. However, studies have not compared the sick leave utilization of vaccinated vs. unvaccinated employees.…”

Section: Introductionmentioning

confidence: 99%

Healthcare workers benefit from second dose of COVID-19 mRNA vaccine: Effects of partial and full vaccination on sick leave duration and symptoms

Unger

2021

Preprint

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ImportanceIn addition to morbidity and mortality of individuals, COVID-19 can affect staffing among organizations. It is important to determine whether vaccination can mitigate this burden. Objective: This study examined the association between COVID-19 vaccination status and time until return to work among 952 healthcare workers (HCW) who tested positive for COVID-19.DesignData were collected prospectively between December 2020 and July 2021. HCW who tested positive for COVID-19 completed an initial interview and were followed until they returned to work.SettingAn academic campus in Southern California consisting of two large hospitals and multiple outpatient clinics and other facilities.ParticipantsClinical and nonclinical HCW who tested positive for COVID-19 during the study period (N=952, mean age=39.2 years, 69% female, 45% Hispanic, 14% white, 14% Asian/Pacific Islander, 5% African American, and 21% other race/ethnicity).ExposureCOVID-19 vaccination status (unvaccinated, partially vaccinated, or fully vaccinated)Main Outcome MeasuresDays until return to work, presenting symptomResultsReturn-to-work time for fully vaccinated HCWs (mean=10.9 days) was significantly shorter than that of partially vaccinated HCWs (15.5 days), which in turn was significantly shorter than that of unvaccinated HCWs (18.0 days). Fully vaccinated HCWs also showed milder symptom profiles compared to partially vaccinated and unvaccinated HCWs.Conclusions and RelevanceCOVID-19 vaccination has the potential to prevent long absences from work and the adverse financial, staffing, and managerial consequences of these long absences.KEY POINTSQuestionDo healthcare workers (HCW) who are vaccinated against COVID-19 return to work sooner and experience milder symptoms compared with unvaccinated HCW?FindingsAmong 952 healthcare workers who tested positive for COVID-19 between December 2020 and July 2021, return-to-work time for fully vaccinated HCWs (mean=10.9 days) was significantly shorter than that of partially vaccinated HCWs (15.5 days), which in turn was significantly shorter than that of unvaccinated HCWs (18.0 days). Fully vaccinated HCWs also showed milder symptom profiles compared to partially vaccinated and unvaccinated HCWs.MeaningCOVID-19 vaccination has the potential to prevent long absences from work and the adverse financial, staffing, and managerial consequences of these long absences.

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COVID-19 Vaccination and Asymptomatic Infection

Cited by 10 publications

References 8 publications

Cumulative Incidence of SARS-CoV-2 in Healthcare Workers at a General Hospital in Germany during the Pandemic—A Longitudinal Analysis

Cumulative Incidence of SARS-CoV-2 in Healthcare Workers at a General Hospital in Germany during the Pandemic—A Longitudinal Analysis

Association between COVID-19 and Sick Leave for Healthcare Workers in a Large Academic Hospital in Southern Italy: An Observational Study

Healthcare workers benefit from second dose of COVID-19 mRNA vaccine: Effects of partial and full vaccination on sick leave duration and symptoms

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