COVID-19 reinforces the need to improve sepsis care resources in Africa

Nsutebu, Emmanuel; Rylance, J.; Appiah, John; Grobusch, Martin P.; Williams, Ged; Kissoon, Niranjan; Elfatih, M Malik; Kabara, Halima; Osman, Khalid; Reinhart, Konrad; Mer, M; Jacob, Shevin T.

doi:10.1007/s15010-020-01571-9

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…A review of cases shows that the proportion of patients diagnosed with COVID-19 and bacterial co-infections was only 6.9% [ 66 ], while over 74% of patients with COVID-19 are treated with antibiotics [ 18 ]. COVID-19 has also brought the limitations of acute medical care in Africa into sharp focus [ 13 ], but how countries across the continent responded to it also demonstrated that early recognition and careful evidence-based care for critically ill patients can drastically reduce mortality.…”

Section: Discussionmentioning

confidence: 99%

“…Amid the global coronavirus pandemic, emerging evidence warns that the most serious complications of COVID-19 include sepsis [ 9 – 13 ]; and COVID-19 reinforces the need to improve sepsis care [ 13 ]. With the emergence of COVID-19, epidemics such as Ebola, Marburg virus disease, Lassa fever, malaria, dengue and measles have also re-emerged in several Low- and Middle-Income Countries (LMICs) [ 7 , 14 – 17 ].…”

Section: Introductionmentioning

confidence: 99%

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On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi

Kawale

Kalitsilo

Mphande

et al. 2022

BMC Health Serv Res

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Sepsis causes 20% of global deaths, particularly among children and vulnerable populations living in developing countries. This study investigated how sepsis is prioritised in Malawi’s health system to inform health policy. In this mixed-methods study, twenty multisectoral stakeholders were qualitatively interviewed and asked to quantitatively rate the likelihood of sepsis-related medium-term policy outcomes being realised. Respondents indicated that sepsis is not prioritised in Malawi due to a lack of local sepsis-related evidence and policies. However, they highlighted strong linkages between sepsis and maternal health, antimicrobial resistance and COVID-19, which are already existing national priorities, and offers opportunities for sepsis researchers as policy entrepreneurs. To address the burden of sepsis, we recommend that funding should be channelled to the generation of local evidence, evidence uptake, procurement of resources and treatment of sepsis cases, development of appropriate indicators for sepsis, adherence to infection prevention and control measures, and antimicrobial stewardship.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi

Kawale

Kalitsilo

Mphande

et al. 2022

BMC Health Serv Res

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“…Foi realizado um estudo na África, associando os resultados favoráveis de pacientes com sepse à disponibilidade de recursos humanos e a infraestrutura de cuidados intensivos adequadamente qualificados. Na África os pacientes que recebem níveis avançados de cuidados intensivos são escassos, devido à falta de recursos para atender a demanda dos cuidados avançados (16) .…”

Section: Springerunclassified

Enfermagem E O Manejo Clínico Em Pacientes Com Sepse Em Uti Covid: Scoping Review

Nascimento¹,

Donini²,

Hortelan³

et al. 2022

Rev. Enferm. Atual In Derme

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Objetivo: Examinar e mapear as evidências científicas sobre o manejo clínico em pacientes sépticos em UTI covid-19. Métodos: Scoping Review, baseado nos procedimentos recomendados pelo Instituto Joanna Briggs. Estabeleceu-se a pergunta norteadora: “Quais são as evidências científicas sobre o manejo clínico de enfermagem em pacientes com sepse na UTI covid?”. Foram realizadas buscas nas seguintes bases de dados: Scielo, PubMed, Lilacs e Portal da Capes, sobre trabalhos publicados até agosto de 2022. Dos 118 estudos encontrados, 06 foram selecionados para leitura na íntegra, resultando em uma amostra final de 05 estudos analisados. Resultados: As cinco publicações analisadas foram publicadas no ano de 2021. Os estudos selecionados sobre a temática são de âmbito nacional e internacional e de abordagens quantitativa, qualitativa e qualiquantitativa. Os objetos dos estudos foram semelhantes, uma vez que a maioria retratava sobre cuidados de enfermagem em pacientes sépticos acometidos pela covid-19. Conclusões: Os resultados desta revisão mostraram uma escassez de estudos nacionais e internacionais sobre a identificação precoce e manejo clínico do paciente séptico acometido pela covid-19. A relevância do tema e sua complexidade evidenciam a necessidade de pesquisas sobre o assunto.

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“…The outcomes of these studies are eagerly awaited. However, there is a need for large-scale quality improvement programs in most African countries, and this can be achieved by development of national action plans for sepsis [ 72 ]. These plans should be developed by national Ministries of Health working with stakeholders such as the Global Sepsis Alliance, African Sepsis Alliance, CDC Africa, African Union and the WHO.…”

Section: Essaymentioning

confidence: 99%

Improving sepsis care in Africa: an opportunity for change?

Keeley¹,

Nsutebu²

2021

Pan Afr Med J

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Sepsis is common and represents a major public health burden with significant associated morbidity and mortality. However, despite substantial advances in sepsis recognition and management in well-resourced health systems, there remains a distinct lack of research into sepsis in Africa. The lack of evidence affects all levels of healthcare delivery from individual patient management to strategic planning at health-system level. This is particular pertinent as African countries experience some of the highest global burden of sepsis. The 2017 World Health Assembly resolution on sepsis and the creation of the Africa Sepsis Alliance provided an opportunity for change. However, progress so far has been frustratingly slow. The recurrent Ebola virus disease outbreaks and the COVID-19 pandemic on the African continent further reinforce the need for urgent healthcare system strengthening. We recommend that African countries develop national action plans for sepsis which should address the needs of all critically ill patients.

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COVID-19 reinforces the need to improve sepsis care resources in Africa

Cited by 3 publications

References 7 publications

On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi

On prioritising global health’s triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi

Enfermagem E O Manejo Clínico Em Pacientes Com Sepse Em Uti Covid: Scoping Review

Improving sepsis care in Africa: an opportunity for change?

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