“…CoroVent was distributed to Czech hospitals. The development of the COVID-19 pandemic revealed that the number of skilled caregivers and intensive care unit spaces rather than available ventilators posed the patient care limitation in many countries 21 . However, ventilator CoroVent was used for ventilation of COVID-19 patients in several exceptional cases in the event of ventilator shortage in the Czech Repubic.…”
Scarcity of medical resources inspired many teams worldwide to design ventilators utilizing different approaches during the recent COVID-19 pandemic. Although it can be relatively easy to design a simple ventilator in a laboratory, a large scale production of reliable emergency ventilators which meet international standards for critical care ventilators is challenging and time consuming. The aim of this study is to propose a novel and easily manufacturable principle of gas mixing and inspiratory flow generation for mechanical lung ventilators. Two fast ON/OFF valves, one for air and one for oxygen, are used to control the inspiratory flow generation using pulse width modulation. Short gas flow pulses are smoothed by low-pass acoustic filters and do not propagate further into the patient circuit. At the same time, the appropriate pulse width modulation of both ON/OFF valves controls the oxygen fraction in the generated gas mixture. Tests focused on the accuracy of the delivered oxygen fractions and tidal volumes have proved compliance with the international standards for critical care ventilators. The concept of a simple construction using two fast ON/OFF valves may be used for designing mechanical lung ventilators and thus suitable for their rapid production during pandemics.
“…CoroVent was distributed to Czech hospitals. The development of the COVID-19 pandemic revealed that the number of skilled caregivers and intensive care unit spaces rather than available ventilators posed the patient care limitation in many countries 21 . However, ventilator CoroVent was used for ventilation of COVID-19 patients in several exceptional cases in the event of ventilator shortage in the Czech Repubic.…”
Scarcity of medical resources inspired many teams worldwide to design ventilators utilizing different approaches during the recent COVID-19 pandemic. Although it can be relatively easy to design a simple ventilator in a laboratory, a large scale production of reliable emergency ventilators which meet international standards for critical care ventilators is challenging and time consuming. The aim of this study is to propose a novel and easily manufacturable principle of gas mixing and inspiratory flow generation for mechanical lung ventilators. Two fast ON/OFF valves, one for air and one for oxygen, are used to control the inspiratory flow generation using pulse width modulation. Short gas flow pulses are smoothed by low-pass acoustic filters and do not propagate further into the patient circuit. At the same time, the appropriate pulse width modulation of both ON/OFF valves controls the oxygen fraction in the generated gas mixture. Tests focused on the accuracy of the delivered oxygen fractions and tidal volumes have proved compliance with the international standards for critical care ventilators. The concept of a simple construction using two fast ON/OFF valves may be used for designing mechanical lung ventilators and thus suitable for their rapid production during pandemics.
“…Patients in the intensive care units, increasingly receive invasive medical devices, which are associated with increased risk for health careassociated infections (HAIS). These infections prolong ICU and hospital stays, raise mortality risk, cause adverse effects, increase antibiotic consumption and inflate the costs of care (Blot et al, 2022& Branson & Rodriquez., 2023. It has been found that approximately (6328) patients admitted annually to intensive care units at assiut university hospitals, that highest of these patients have HAIs.…”
Background: Several invasive devices are connected daily in intensive care patients. It is evident that complications associated with these invasive devices and are potentially life threatening. Aim of the study: Explore the effect of invasive devices on occurrence of complications and mortality rate among intensive care patients
“…One of the treatments in the initial stage of the COVID-19 pandemic is the application, to patients with respiratory disorders, of mechanical ventilator that is based on an internal compressor and mixer to moderate and control the gas mixture delivered to ill patients. Nevertheless, a major problem was the shortage of these breathing machines [ [15] , [16] , [17] ]. Jones [ 18 ] argues that in India only 50% of intensive care units has a mechanical ventilator.…”
Section: Introductionmentioning
confidence: 99%
“…This technological approach reduces many physical components present in traditional ventilators, shortens the time from storage to clinical deployment, improves reliability in terms of life-saving ventilatory support, satisfying emergency guidelines of the U.S. FDA. Planners and policymakers also realized that during COVID-19 pandemic crisis, the technical personnel to operate mechanical ventilation was another elements of shortage [ 15 ]. Jimenez-Maturano and Licona [ 26 ] maintain that the demand increase for the production of ventilation machines can create risks concerning the correct equipment's operation and effective safety to care for COVID-19 patients.…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.