High potential of technology to face new respiratory viruses: mechanical ventilation devices for effective healthcare to next pandemic emergencies

Coccia, Mario

doi:10.1016/j.techsoc.2023.102233

Cited by 23 publications

(18 citation statements)

References 93 publications

(106 reference statements)

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“…The COVID-19 pandemic showed that there is a lot to learn and to improve in our ability to face the fast spread of a pathogenic agent and manage future crisis scenarios (Coccia 2021 ). Vaccination was the main pharmaceutical measure that leads to a reduction in the number of infected individuals and lethal cases (Coccia 2022b , c ), and it has been shown that good governance can increase vaccination levels (Benati and Coccia 2022a ) Among non-pharmaceutical measures for crisis management, aside from more effective new technologies (Coccia 2023 ), the most common social policies adopted where lockdowns, which were effective but restricted the population mobility (Alfano and Ercolano 2020 ; Cai et al 2021 ; Secco and Conte 2022 ) and contact tracing (Benati and Coccia 2022b ), which were less widely adopted in countries with limited resources as Brazil. It has been argued that the adoption of more comprehensive prevention strategies in the case of new epidemics in the future must also be based on sustainability and environmental sciences (Coccia 2020 ).…”

Section: Conclusion Limitations and Prospectsmentioning

confidence: 99%

20-Month monitoring of SARS-CoV-2 in wastewater of Curitiba, in Southern Brazil

Belmonte-Lopes,

Barquilha,

Kozak

et al. 2023

Environ Sci Pollut Res

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The COVID-19 pandemic resulted in the collapse of healthcare systems and led to the development and application of several approaches of wastewater-based epidemiology to monitor infected populations. The main objective of this study was to carry out a SARS-CoV-2 wastewater based surveillance in Curitiba, Southern Brazil Sewage samples were collected weekly for 20 months at the entrance of five treatment plants representing the entire city and quantified by qPCR using the N1 marker. The viral loads were correlated with epidemiological data. The correlation by sampling points showed that the relationship between the viral loads and the number of reported cases was best described by a cross-correlation function, indicating a lag between 7 and 14 days amidst the variables, whereas the data for the entire city presented a higher correlation (0.84) with the number of positive tests at lag 0 (sampling day). The results also suggest that the Omicron VOC resulted in higher titers than the Delta VOC. Overall, our results showed that the approach used was robust as an early warning system, even with the use of different epidemiological indicators or changes in the virus variants in circulation. Therefore, it can contribute to public decision-makers and health interventions, especially in vulnerable and low-income regions with limited clinical testing capacity. Looking toward the future, this approach will contribute to a new look at environmental sanitation and should even induce an increase in sewage coverage rates in emerging countries. Supplementary Information The online version contains supplementary material available at 10.1007/s11356-023-27926-x.

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Section: Conclusion Limitations and Prospectsmentioning

confidence: 99%

20-Month monitoring of SARS-CoV-2 in wastewater of Curitiba, in Southern Brazil

Belmonte-Lopes,

Barquilha,

Kozak

et al. 2023

Environ Sci Pollut Res

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“…Despite these limitations, the results here clearly illustrate statistically significant associations between some meteorological factors and COVID-19 cases in specific cities, and an elaborate and partial role of weather humidity, when considered in isolation, in explaining high levels of diffusion of the COVID-19. Policymakers should consider these results for the designing of effective control measures and health policies based on a systemic approach with manifold social and environmental factors, to minimize the negative effects of future variants of SARS-CoV-2 and/or new viral agents [11,27,28,[59][60][61][62][63]. To conclude, a systemic approach for the evaluation of all interactions between meteorological, environmental, and socioeconomic factors can explain the effective transmission dynamics of new viral agents to improve pandemic crisis plans aimed at facing unknown infectious diseases similar to COVID-19 that we know will occur in the future, even if we do not know when.…”

Section: Conclusion Limitations and Prospectsmentioning

confidence: 99%

“…In 2023, the negative effects of the Coronavirus Disease 2019 (COVID-19) pandemic are considerably reduced, unlike during the early period of 2020, though many nations and people still have to cope with COVID-19 illnesses driven by new variants [1][2][3][4][5][6][7][8][9]. Numerous studies have focused on identifying the factors that determine the spread of COVID-19 with mutant viral agents [10,11]. Studies show that transmission of COVID-19 can be caused by direct contact (in droplets through person-to-person interactions) or indirect transmission (through contaminated objects or air) [12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Transmission of COVID-19 in Cities with Weather Conditions of High Air Humidity: Lessons Learned from Turkish Black Sea Region to Face Next Pandemic Crisis

Akan,

Coccia

2023

COVID

Self Cite

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The goal of this study is to analyze associations between COVID-19 transmission and meteorological indicators in cities of the Black Sea region of Turkey, located specifically in the dampest area, with excess rainfall and recurring fog. In particular, the working hypothesis is that the widespread transmission of new coronavirus SARS-CoV-2 (leading to the airborne disease COVID-19) in cities can be explained by specific weather conditions, namely high levels of air humidity. Statistical evidence here does not seem, in general, to support the hypothesis that the accelerated transmission of COVID-19 in the studied cities can be explained by high levels of humidity because different meteorological, environmental, demographic, and socioeconomic factors also plays a critical role in the disease transmission dynamics of the investigated region. The main implications of our findings here are that the demographic structure of the population, climate indicators, organization of the health system, and environmental factors (e.g., air pollution, etc.) should be considered through a systemic approach when designing effective national and regional pandemic plans directed to implement health policies for facing new variants of COVID-19 and/or new airborne diseases, in order to reduce their negative effects on health, social and economic systems.

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“…This can happen in poorly ventilated spaces where the virus can accumulate and remain suspended in the air for longer periods (Coccia. 2023a ).…”

Section: Introductionmentioning

confidence: 99%

Determining half-life of SARS-CoV-2 antigen in respiratory secretion

Guang

Liu

2023

Environ Sci Pollut Res

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is primarily transmitted from person to person through respiratory droplets and aerosols. It is also possible for the virus to be transmitted indirectly through environmental contamination. The likelihood of environmental transmission depends on several factors, including the survival time of the virus in respiratory secretions. However, the stability of SARS-CoV-2 in respiratory secretions has not been investigated. In this study, we compared the half-life of the SARS-CoV-2 antigen in respiratory secretion under different conditions. We applied respiratory secretion (5 µL) to glass slides, air-dried the slides for 1 h, and kept them at 24 °C or 4 °C for 10 days. Respiratory secretions were also placed in test tubes (sealed to preserve moisture) and in normal saline for 10 days. The concentration of SARS-CoV-2 antigen in all samples was simultaneously measured using colloidal gold immunochromatography, and the half-life of the antigen was calculated. The half-life of the antigen in the wet (sealed tube) and saline samples at room temperature was 5.0 and 2.92 days, respectively. The half-life of the antigen in the air-dried sample at room temperature and at 4 °C was 2.93 and 11.4 days, respectively. The half-life was longer in respiratory secretions than that in normal saline. The half-life was also longer in respiratory secretions, at a lower temperature, and under wet conditions. Therefore, environmental transmission can also play a significant role in the spread of the virus. Robust prevention and control strategies could be developed based on the half-life of the antigen in respiratory secretions.

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High potential of technology to face new respiratory viruses: mechanical ventilation devices for effective healthcare to next pandemic emergencies

Cited by 23 publications

References 93 publications

20-Month monitoring of SARS-CoV-2 in wastewater of Curitiba, in Southern Brazil

20-Month monitoring of SARS-CoV-2 in wastewater of Curitiba, in Southern Brazil

Transmission of COVID-19 in Cities with Weather Conditions of High Air Humidity: Lessons Learned from Turkish Black Sea Region to Face Next Pandemic Crisis

Determining half-life of SARS-CoV-2 antigen in respiratory secretion

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