COVID-19 in pregnancy: a systematic review of chest CT findings and associated clinical features in 427 patients

Oshay, Rachel R.; Chen, Michael Y.C.; Fields, Brandon; Demirjian, Natalie L.; Lee, Ryan S.; Mosallaei, Daniel; Gholamrezanezhad, Ali

doi:10.1016/j.clinimag.2021.01.004

Cited by 25 publications

(26 citation statements)

References 101 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Maternal mortality was reported in 39 SRs, [ 16 , 17 , 18 , 20 , 21 , 22 , 23 , 25 , 34 , 35 , 36 , 39 , 40 , 41 , 46 , 47 , 51 , 52 , 54 , 55 , 57 , 60 , 62 , 63 , 64 , 65 , 67 , 68 , 72 , 73 , 74 , 76 , 77 , 78 , 79 , 80 , 87 , 88 ] and varied from 0% to 11.1% among the included reviews.…”

Section: Resultsmentioning

confidence: 99%

Vertical Transmission of SARS-CoV-2: A Systematic Review of Systematic Reviews

Musa

Bello

Zhao

et al. 2021

Viruses

View full text Add to dashboard Cite

The COVID-19 pandemic has hugely impacted global public health and economy. The COVID-19 has also shown potential impacts on maternal perinatal and neonatal outcomes. This systematic review aimed to summarize the evidence from existing systematic reviews about the effects of SARS-CoV-2 infections on maternal perinatal and neonatal outcomes. We searched PubMed, MEDLINE, Embase, and Web of Science in accordance with PRISMA guidelines, from 1 December 2019 to 7 July 2021, for published review studies that included case reports, primary studies, clinical practice guidelines, overviews, case-control studies, and observational studies. Systematic reviews that reported the plausibility of mother-to-child transmission of COVID-19 (also known as vertical transmission), maternal perinatal and neonatal outcomes, and review studies that addressed the effect of SARS-CoV-2 infection during pregnancy were also included. We identified 947 citations, of which 69 studies were included for further analysis. Most (> 70%) of the mother-to-child infection was likely due to environmental exposure, although a significant proportion (about 20%) was attributable to potential vertical transmission of SARS-CoV-2. Further results of the review indicated that the mode of delivery of pregnant women infected with SARS-CoV-2 could not increase or decrease the risk of infection for the newborns (outcomes), thereby emphasizing the significance of breastfeeding. The issue of maternal perinatal and neonatal outcomes with SARS-CoV-2 infection continues to worsen during the ongoing COVID-19 pandemic, increasing maternal and neonatal mortality, stillbirth, ruptured ectopic pregnancies, and maternal depression. Based on this study, we observed increasing rates of cesarean delivery from mothers with SARS-CoV-2 infection. We also found that SARS-CoV-2 could be potentially transmitted vertically during the gestation period. However, more data are needed to further investigate and follow-up, especially with reports of newborns infected with SARS-CoV-2, in order to examine a possible long-term adverse effect.

show abstract

Section: Resultsmentioning

confidence: 99%

Vertical Transmission of SARS-CoV-2: A Systematic Review of Systematic Reviews

Musa

Bello

Zhao

et al. 2021

Viruses

View full text Add to dashboard Cite

show abstract

“…11 Chest radiographs may be normal in early or mild disease. In a systematic review by Oshay et al 12 in 427 pregnant patients diagnosed with COVID-19, the most frequently encountered pulmonary findings on chest computed tomography were groundglass opacities (77%), posterior lung involvement (73%), multilobar involvement (72%), bilateral lung involvement (69%), peripheral distribution (68%), and consolidation (41%). Our hospital was converted in emergency to a COVID facility so only X-ray facilities A systematic review by Allotey et al 9 including over 11,000 pregnant and recently pregnant women with suspected or confirmed COVID-19 reported that 17% delivered before 37 weeks and 65% delivered by cesarean.…”

Section: Materials a N D Methodsmentioning

confidence: 99%

Characteristics and Outcomes of COVID-19 (SARS-CoV-2)Positive Pregnant Women Admitted to a Dedicated COVID Hospital in Central India: A Single-center Observational Study

Gupta¹,

Dave²,

Avashia³

et al. 2021

Journal of South Asian Federation of Obstetrics and Gynaecology

View full text Add to dashboard Cite

“…According to the results of a systematic review including 427 pregnant women with COVID-19, ground-glass opacities (77%), posterior lung involvement (73%), multilobar involvement (72%), bilateral lung involvement (69%), peripheral distribution (68%), and consolidation (41%) were the most common pathologic findings in the computerized tomography (CT) [30]. Radiologic imaging was performed in 12.7% of the pregnant women and 57.3% of them were suspicious for COVID-19 according to the results of a prospective study from Turkey [26].…”

Section: Radiologic Imaging and Laboratory Findingsmentioning

confidence: 99%

Pregnancy and COVID-19: prevention, vaccination, therapy, and beyond

Şahın¹,

Webster²,

Tekın³

2021

Turk J Med Sci

View full text Add to dashboard Cite

Coronavirus disease 2019 (COVID-19) caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has alarmed the world since its first emergence. As pregnancy is characterized by significant changes in cardiovascular, respiratory, endocrine and immunological systems, there are concerns on issues like the course of disease in pregnant women, safety of medications, route of delivery and risk of obstetric complications. The aim of this review is to summarize the current literature in the management of pregnant women during the COVID-19 pandemic. Although more than 90% of pregnant women with COVID-19 recover without serious morbidity, rapid deterioration of disease and higher rates of obstetric complications may be observed. The risk of vertical transmission has not been clearly revealed, yet. Decreasing the number of prenatal visits, shortening the time allocated for the examinations, active use of telemedicine services, limiting the number of persons in health-care settings, combining prenatal tests in the same visit, restricting visitors during the visits, providing a safe environment in health-care facilities, strict hygene control and providing personal protective equipment during the visits are the main strategies to control the spread of disease according to current guidelines. Although new medication alternatives are being proposed every day for the treatment of COVID-19, our knowledge about the use of most of these drugs in pregnancy is limited. Preliminary results are promising for the administration of SARS-CoV-2 vaccines in the pregnant population. Timing of delivery should be decided based on maternal health condition, accompanying obstetric complications and gestational age. Cesarean delivery should be performed for obstetric indications. Breast feeding should be encouraged as long as necessary precautions for viral transmission are

show abstract

COVID-19 in pregnancy: a systematic review of chest CT findings and associated clinical features in 427 patients

Cited by 25 publications

References 101 publications

Vertical Transmission of SARS-CoV-2: A Systematic Review of Systematic Reviews

Vertical Transmission of SARS-CoV-2: A Systematic Review of Systematic Reviews

Characteristics and Outcomes of COVID-19 (SARS-CoV-2)Positive Pregnant Women Admitted to a Dedicated COVID Hospital in Central India: A Single-center Observational Study

Pregnancy and COVID-19: prevention, vaccination, therapy, and beyond

Contact Info

Product

Resources

About