COVID‐19 disease in New York City pediatric hematology and oncology patients

Gampel, B.; Lucas, Alexandre; Broglie, Larisa; Gartrell‐Corrado, Robyn D.; Lee, Margaret T.; Levine, Jennifer; Orjuela‐Grimm, Manuela; Satwani, Prakash; Bender, Julia Glade; Roberts, Stephen S.

doi:10.1002/pbc.28420

Cited by 57 publications

(79 citation statements)

References 10 publications

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“…2 This recommendation coincides with that of Liang et al adult patients, based on a greater severity of SARS-CoV-2 observed in cancer patients in China. 8 However, these recommendations were made in the first months of the pandemic and now with the different reports around the world [4][5][6][7]9 which informed a favourable evolution in most patients, the decision to postpone or stop treatment should be reconsidered. Unfortunately reports from countries like Mexico are scarce 10 and it is difficult to predict that most cases of COVID-19 in children with cancer will recover with no complications.…”

Section: Discussionmentioning

confidence: 99%

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Children with cancer during COVID-19 pandemic. Early experience in Mexico.

López-Aguilar¹,

Cárdenas-Navarrete²,

Toba³

et al. 2020

Preprint

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Reports of children with cancer and COVID-19 from U.S.A and Europe had informed most patients presented with mild disease. Experience from upper and lower middle-income countries is needed to corroborate these findings. This report describes the experience with cancer patients in a tertiary care level hospital, in Mexico City. Of 24 symptomatic patients, 14 had a positive RT-PCR test. Eight required low-flow supplemental oxygen. None required critical care. One patient died due to pulmonary hemorrhage. Even though the infection seems to have an uncomplicated clinical course, it is necessary to ensure that all seeking medical attention do so safely.

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Section: Discussionmentioning

confidence: 99%

“…Reports of children with cancer from U.S.A and Italy had informed most of the affected patients had a mild disease and very few of them required critical care. [4][5][6][7] The aim of this report is to share the experience with cancer patients cared for in a tertiary care level hospital, in Mexico City.…”

Section: Introductionmentioning

confidence: 99%

Children with cancer during COVID-19 pandemic. Early experience in Mexico.

López-Aguilar¹,

Cárdenas-Navarrete²,

Toba³

et al. 2020

Preprint

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“…Pediatric patients with cancer are at a higher risk of lifethreatening complications from respiratory viral infections and their incidence of coinfection is higher than that of the general pediatric population. 79 While several reports have documented that adult oncology patients are at higher risk of complications from COVID-19 than those without cancer, 80,81 the impact of SARS-CoV-2 on children with malig- 84 In a study from Peru, almost half of 69 pediatric patients with cancer presented asymptomatic SARS-CoV-2 infection. 85 The most common clinical manifestations in symptomatic infection were fever and cough.…”

Section: Covid-19 Infection In Pediatric Oncology Patientsmentioning

confidence: 99%

Hematological manifestations of SARS‐CoV‐2 in children

Kosmeri

Koumpis

Tsabouri

et al. 2020

Pediatric Blood & Cancer

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Infection from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), though mainly a respiratory disease, can impair many systems, including causing hematological complications. Lymphopenia and hypercoagulability have been reported in adults with coronavirus disease 2019 (COVID-19) and are considered markers of poor prognosis. This review summarizes the hematological findings in children with SARS-CoV-2 infection. The majority of infected children had a normal leukocyte count, while the most common white blood cell abnormality was leukopenia. Lymphopenia, which may be a marker of severe disease, was rarer in children than in adults, possibly due to their immature immune system or due to the less severe manifestation of COVID-19 in this age group. Age may have an impact, and in neonates and infants the most common abnormality was lymphocytosis. Abnormalities of red blood cells and platelets were uncommon. Anemia and hypercoagulability were reported mainly in children presenting the novel multisystem inflammatory syndrome (MIS) associated with SARS-CoV-2.

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“…States and Italy had informed that most of the affected patients had a mild disease and very few of them required critical care. [3][4][5][6] The aim of this report is to share the experience with cancer patients cared for in a tertiary care level hospital in Mexico City. of SARS-CoV-2 observed in cancer patients in China.…”

Section: Reports Of Children With Cancer From Unitedmentioning

confidence: 99%