Covid-19-Associated Diffuse Alveolar Hemorrhage: A Case Report

Ji, Sophia; Singh, Parmanand; Rhee, Christina Jee Ah; Izakovich, Tereza; Gumpeni, Rammohan; Castañeda, Christian

doi:10.1016/j.chest.2021.07.1860

Cited by 2 publications

(3 citation statements)

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“…Our patient presented in her neonatal period with pulmonary hemorrhage, which has been reported in adults, but rarely in children with COVID‐19 infection 8 . It is such a diagnostic challenge because it can be caused by multiple alternative diagnoses, such as chest infections and ANCA vasculitis.…”

Section: Discussionmentioning

confidence: 75%

“…7 Our patient presented in her neonatal period with pulmonary hemorrhage, which has been reported in adults, but rarely in children with COVID-19 infection. 8 It is such a diagnostic challenge because it can be caused by multiple alternative diagnoses, such as chest infections and ANCA vasculitis. However, history, examination, and workup can give a clue to whether the pulmonary hemorrhage is caused by diseases other than COVID-19 infection.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Severe pulmonary hemorrhage in a 3‐week‐old neonate with COVID‐19 infection: A case report

Alassaf

Ellithy

Mehta

et al. 2022

Clinical Case Reports

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Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 99%

Severe pulmonary hemorrhage in a 3‐week‐old neonate with COVID‐19 infection: A case report

Alassaf

Ellithy

Mehta

et al. 2022

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

“…Laboratory findings for DAH can be nonspecific, and, thus, diagnostic testing typically focuses on assessing potentially related symptoms, such as bleeding disorders, or concurrent kidney disease, while also considering historical and physical examination clues regarding underlying causes. Additionally, in cases of suspected DAH, it is imperative to meticulously explore other possible infectious etiologies, including bacterial pneumonia and COVID-19 [9].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Diffuse Alveolar Hemorrhage Caused by Fentanyl Inhalation

Nangrani,

Chung,

Jyang

et al. 2023

Cureus

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Diffuse alveolar hemorrhage (DAH) is a rare but life-threatening pulmonary disorder characterized by blood accumulation in alveolar spaces, often associated with autoimmune diseases and infections. Drug-induced causes of DAH, including inhalation of substances like fentanyl, are emerging concerns. A 40-year-old male with bipolar disorder and polysubstance abuse presented with altered mental status and hemoptysis after inhaling an unknown substance. Physical examination revealed respiratory distress, pinpoint pupils, and severe hypoxemia. Naloxone administration improved his condition. The workup showed negative infection markers, positive fentanyl-specific urine test, and diffuse bilateral opacities on imaging. Bronchoalveolar lavage confirmed DAH with >20% hemosiderin-laden macrophages. Steroid treatment resulted in marked improvement. Drug-induced DAH, such as fentanyl inhalation, should be considered in patients with altered mental status and pulmonary symptoms following substance use. Comprehensive evaluation and targeted treatment are crucial for optimal outcomes.

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Covid-19-Associated Diffuse Alveolar Hemorrhage: A Case Report

Cited by 2 publications

References 0 publications

Severe pulmonary hemorrhage in a 3‐week‐old neonate with COVID‐19 infection: A case report

Severe pulmonary hemorrhage in a 3‐week‐old neonate with COVID‐19 infection: A case report

A Rare Case of Diffuse Alveolar Hemorrhage Caused by Fentanyl Inhalation

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