COVID-19−Associated Decline in the Size of the End-Stage Kidney Disease Population in the United States

Weinhandl, Eric D.; Gilbertson, David T.; Wetmore, James B.; Johansen, Kirsten L.

doi:10.1016/j.ekir.2021.07.019

Cited by 20 publications

(19 citation statements)

References 6 publications

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“… The initial weeks of the pandemic in early 2020 were associated with a decrease in the total number of individuals registered with new onset chronic kidney failure requiring KRT. In April 2020 in the USA, there was a 25% decrease in the incidence of kidney failure relative to historical projections; by 1 year after the start of the pandemic, there were about 3.5% fewer KRT patients in the USA than would have been projected 90 , 91 . Possible explanations include high mortality of patients with pre-dialysis CKD from COVID-19.…”

Section: Covid-19 and Chronic Kidney Diseasementioning

confidence: 95%

“…This inverse relationship may reflect mortality as a competing outcome, whereby many patients with CKD who, without COVID-19, would have progressed to chronic dialysis, instead died. There were also reduced rates of transplantation, which contributed to delayed haemodialysis initiation in some settings due to a lack of capacity 90 , 91 .…”

Section: Covid-19 and Kidney Outcomes In The General Populationmentioning

confidence: 99%

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COVID-19 and kidney disease: insights from epidemiology to inform clinical practice

Mahalingasivam

Iwagami

et al. 2022

Nat Rev Nephrol

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Over the course of the COVID-19 pandemic, numerous studies have aimed to address the challenges faced by patients with kidney disease and their caregivers. These studies addressed areas of concern such as the high infection and mortality risk of patients on in-centre haemodialysis and transplant recipients. However, the ability to draw meaningful conclusions from these studies has in some instances been challenging, owing to barriers in aspects of usual care, data limitations and problematic methodological practices. In many settings, access to SARS-CoV-2 testing differed substantially between patient groups, whereas the incidence of SARS-CoV-2 infection varied over time and place because of differences in viral prevalence, targeted public health policies and vaccination rates. The absence of baseline kidney function data posed problems in the classification of chronic kidney disease and acute kidney injury in some studies, potentially compromising the generalizability of findings. Study findings also require attentive appraisal in terms of the effects of confounding, collider bias and chance. As this pandemic continues and in the future, the implementation of sustainable and integrated research infrastructure is needed in settings across the world to minimize infection transmission and both prevent and plan for the short-term and long-term complications of infectious diseases. Registries can support the real-world evaluation of vaccines and therapies in patients with advanced kidney disease while enabling monitoring of rare complications.

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Section: Covid-19 and Chronic Kidney Diseasementioning

confidence: 95%

Section: Covid-19 and Kidney Outcomes In The General Populationmentioning

confidence: 99%

COVID-19 and kidney disease: insights from epidemiology to inform clinical practice

Mahalingasivam

Iwagami

et al. 2022

Nat Rev Nephrol

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“…Together, these events brought about the first substantial shrinkage in the ESRD population. 3 Initiation of in-facility hemodialysis declined to a greater extent than initiation of peritoneal dialysis, leading to an increase in the percentage of new ESRD patients starting peritoneal dialysis that was not accompanied by an increase in new peritoneal dialysis starts. 2 …”

Section: Data Sourcesmentioning

confidence: 99%

US Renal Data System 2021 Annual Data Report: Epidemiology of Kidney Disease in the United States

Johansen¹,

Chertow²,

Gilbertson³

et al. 2022

American Journal of Kidney Diseases

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164

107

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“…Although regional disparities were observed, in the US the number of incident patients and the mean estimated glomerular filtration rate at dialysis initiation were significantly lower in 2020 than in previous years, particularly in elderly patients and non-Hispanic Blacks 27 , 28 . Overall, the size of the US dialysis population shrunk by 1,6% in 2020 29 .…”

Section: Disease Coursementioning

confidence: 99%

COVID-19 in dialysis: clinical impact, immune response, prevention, and treatment

Karoui

Vriese

2022

Kidney International

106

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COVID-19−Associated Decline in the Size of the End-Stage Kidney Disease Population in the United States

Cited by 20 publications

References 6 publications

COVID-19 and kidney disease: insights from epidemiology to inform clinical practice

COVID-19 and kidney disease: insights from epidemiology to inform clinical practice

US Renal Data System 2021 Annual Data Report: Epidemiology of Kidney Disease in the United States

COVID-19 in dialysis: clinical impact, immune response, prevention, and treatment

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