Coverage of Miller Class I and II Recession Defects Using Enamel Matrix Proteins Versus Coronally Advanced Flap Technique: A 2‐Year Report

Spahr, Axel; Haegewald, Stefan; Tsoulfidou, F; Rompola, Eirini; Heijl, Lars; Bernimoulin, Jean‐Pierre; Ring, Christina; Sander, Silvia; Haller, Bernd

doi:10.1902/jop.2005.76.11.1871

Cited by 72 publications

(139 citation statements)

References 49 publications

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“…They obtained slightly better outcomes with CPF‫ם‬EMD in terms of root coverage and clinical attachment level than with CPF, but the differences were not statistically significant. Other studies 6,7,20) involving more cases and longer follow-up periods also found no significant differences between CPF and CPF‫ם‬EMD. Meanwhile, several studies 3,5,18) have shown significantly better outcomes with CPF‫ם‬EMD than with CPF in terms of percentage of root coverage, keratinized gingival gain, and attachment gain, revealing substantial variability in the outcomes of long-term studies of CPF‫ם‬EMD.…”

Section: Discussionmentioning

confidence: 82%

Root Coverage Technique with Enamel Matrix Derivative

Moriyama

Matsumoto

Makiishi

2009

Bull. Tokyo Dent. Coll.

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Various periodontal plastic surgical techniques are employed in obtaining root coverage. Recently, the use of an enamel matrix derivative (EMD) has been reported in such treatment. We report 2 cases of root coverage surgery with a coronally positioned flap in combination with EMD (CPF‫ם‬EMD) and connective tissue graft in combination with EMD (CTG‫ם‬EMD). Case 1: The patient was a 25-year-old woman referred to Suidobashi Hospital, Tokyo Dental College for root coverage surgery on the lower right first premolar. Gingival recession was classified as Miller Class II, as no alveolar bone loss or loss of attachment was observed in the interdental area, although recession had progressed to the mucogingival junction. The patient was diagnosed with local gingival recession caused by excessive tooth brushing. Primary conservative treatment failed to reduce the gingival recession. Subsequently, root coverage surgery with CPF‫ם‬EMD was carried out. As observation at the 1-year follow-up revealed complete root coverage and no recurrence of root exposure or subjective symptoms, the postoperative course was considered to be favorable. Case 2: The patient was a 39-year-old woman referred to Suidobashi Hospital, Tokyo Dental College for root coverage surgery on the lower left canine. Gingival recession was classified as Miller Class II. Root coverage surgery with CTG‫ם‬EMD was carried out. As observation at the 2-month follow-up revealed complete root coverage and no recurrence of root exposure, the postoperative course was considered to be favorable. These 2 cases indicate the effectiveness of root coverage surgery with CPF‫ם‬EMD and CTG‫ם‬EMD.

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Section: Discussionmentioning

confidence: 82%

Root Coverage Technique with Enamel Matrix Derivative

Moriyama

Matsumoto

Makiishi

2009

Bull. Tokyo Dent. Coll.

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“…This regenerative concept has also been demonstrated in root coverage procedures (24). EMD associated with CAF was shown to increase the percentage of root coverage (25).…”

Section: Introductionmentioning

confidence: 86%

Application of subepithelial connective tissue graft with or without enamel matrix derivative for root coverage: a split-mouth randomized study

et al. 2010

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“…Additional application of EMD, however, induced a statistically significantly greater formation of keratinized tissue, compared to that with coronally positioned flap alone [130] . A follow-up evaluation of this study showed that over 2 years, complete root coverage could be maintained in 53% of the EMD group compared to the control (23%) [131] . However, in the second year after therapy as many as 47% of the control group had deteriorated compared to only 22% in the treatment group.…”

Section: Controlled Clinical Studies In Recession Defectsmentioning

confidence: 66%

“…The available data suggest that the use of EMD may enhance the outcome of root coverage procedures, but the additional application of a connective tissue graft seems to further enhance the formation of keratinized tissue [134][135][136] . It is interesting to note that most controlled clinical studies evaluating the treatment of gingival recessions with coronally repositioned flaps and EMD therapy reported stable clinical results after a longer time period, up to 2 years, and an increase in the width of keratinized tissue, thus indicating that EMD may have an effect upon the proliferation and keratinization of gingival fibroblasts [131,137,138] .…”

Section: Controlled Clinical Studies In Recession Defectsmentioning

confidence: 99%

The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

et al. 2007

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Regenerative periodontal therapy aims at reconstitution of the lost periodontal structures such as new formation of root cementum, periodontal ligament and alveolar bone. Findings from basic research indicate that enamel matrix protein derivative (EMD) has a key role in periodontal wound healing. Histological results from animal and human studies have shown that treatment with EMD promotes periodontal regeneration. Moreover, clinical studies have indicated that treatment with EMD positively influences periodontal wound healing in humans. This review aims to present an overview of evidence-based clinical indications for regenerative therapy with EMD.

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Coverage of Miller Class I and II Recession Defects Using Enamel Matrix Proteins Versus Coronally Advanced Flap Technique: A 2‐Year Report

Abstract: Enamel matrix derivative seems to provide better long-term results.

Cited by 72 publications

References 49 publications

Root Coverage Technique with Enamel Matrix Derivative

Root Coverage Technique with Enamel Matrix Derivative

Application of subepithelial connective tissue graft with or without enamel matrix derivative for root coverage: a split-mouth randomized study

The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

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