Course of rotavirus gastroenteritis in a closed community.

Morishima, Tsuneo; Yamaguchi, Hideaki; Nagayoshi, Shoichi; Ozaki, Takao; Isomura, Shin; Suzuki, Sakae

doi:10.1136/adc.55.2.147

Cited by 6 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This protection extends to rotaviral gastroenteritis, at least to some extent, as lower incidences of viral diarrhoea have been found in breast fed infants.2 Newborns and infants in general under 6 months of age have been shown to have mild or asymptomatic rotaviral infection. 3 Gut associated lymphoid tissue (as the local defence mechanism against this virus) consists of Peyer's patches and other lymphoid tissues in the intestine, including mesenteric lymph nodes. After antigenic stimulation in the gut primed B cells, particularly cells that produce IgA, can migrate from there to various sites of external secretions, such as breast tissue, to produce local antibody there.4 This study was undertaken to determine the reason for relative resistance to rotaviral gastroenteritis in the newborn period by estimating the antibody transfer from the mother and also to explore the role of maternal gut associated lymphoid tissue against neonatal rotavirus infection.…”

mentioning

confidence: 99%

Local production of rotavirus specific IgA in breast tissue and transfer to neonates.

Rahman¹,

Yamauchi²,

Hanada³

et al. 1987

Archives of Disease in Childhood

Self Cite

View full text Add to dashboard Cite

mentioning

confidence: 99%

Local production of rotavirus specific IgA in breast tissue and transfer to neonates.

Rahman¹,

Yamauchi²,

Hanada³

et al. 1987

Archives of Disease in Childhood

Self Cite

View full text Add to dashboard Cite

“…A temporary failure of bile emulsification, possibly with a defect in absorption was thought likely. Deficiency of pigment, but not steatorrhoea, has been described in the stools of children with rotavirus infection in Japan where the condition is known as 'Hakuri' (Konno et al 1977;Morishima et al 1980). …”

Section: Discussionmentioning

confidence: 99%

Virus diarrhoea associated with pale fatty faeces

Thomas

Luton

Mortimer

1981

J. Hyg.

View full text Add to dashboard Cite

SUMMARYSteatorrhoea was a significant feature in an outbreak of rotavirus gastroenteritis which affected adults and infants in hospital. Fat globules or fatty acid crystals were obvious by light microscopy (LM) in faeces from 14 of 25 patients examined. Ten of the fatty stools and two of the remainder were very pale. By electron microscopy (EM) a rotavirus was seen in 11 of the 14 fatty faeces and in only two of 11 specimens without visible fat.In a further study of pale or fatty faeces 20 such specimens sent for laboratory examination from patients not involved in the hospital outbreak were compared microbiologically with a similar number which were neither pale nor fatty. Viruses were found by EM in 11 (55 %) of the pale or fatty stools; eight rotaviruses, two astroviruses and an uncultivable adenovirus were seen; one further patient had acute jaundice. In contrast, no viruses were seen by EM in the twenty specimens which were normally pigmented and without evident fat.Steatorrhoea was significantly associated with rotavirus infection of the alimentary tract which usually presented as a fatty enteritis. We conclude that rotaviruses certainly, and other viruses possibly, can impede both the digestion of fat and the pigmentation of the faeces. Inspection and LM of faeces are easy. In acute enteritis a fatty or pale stool is an indication for virological examination.

show abstract

Rotavirus gastroenteritis

2005

View full text Add to dashboard Cite

Rotavirus is the single most important cause of severe, dehydrating gastroenteritis in infants and young children worldwide. Rotavirus gastroenteritis is associated with high morbidity in developed countries and significant mortality in developing countries. Virtually all children are infected with rotavirus by 3 years of age. Fecal-oral transmission is the most likely route of virus spread. Group A serotype strains G1 through G4 account for more than 90% of rotavirus gastroenteritis in humans, with G1 being the predominant serotype. The virus preferentially infects the mature small-intestinal enterocytes. Rotavirus gastroenteritis is characterized by fever, vomiting, and diarrhea, with vomiting particularly prominent. Dehydration is a frequent complication because of the severity of the diarrhea and the associated vomiting. Rehydration and maintenance of proper fluid and electrolyte balance remain the mainstay of treatment. Hygienic measures have little effect on the reduction of rotavirus infection rates. The disease can be effectively controlled by universal rotavirus vaccination.

show abstract

Course of rotavirus gastroenteritis in a closed community.

Cited by 6 publications

References 8 publications

Local production of rotavirus specific IgA in breast tissue and transfer to neonates.

Local production of rotavirus specific IgA in breast tissue and transfer to neonates.

Virus diarrhoea associated with pale fatty faeces

Rotavirus gastroenteritis

Contact Info

Product

Resources

About