Coupling solid-phase microextraction and high-performance liquid chromatography for direct and sensitive determination of halogenated fungicides in wine

Millán, Silvia; Sampedro, M. Carmen; Unceta, Nora; Goicolea, M. Aránzazu; Rodríguez, Esther; Barrio, Ramón J.

doi:10.1016/s0021-9673(03)00521-1

Cited by 65 publications

(33 citation statements)

References 28 publications

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“…In our case, we observed that the addition of salt did not produce an enhancement of the extraction and as previously reported [36], no direct relation between extraction efficiency and salt content was found. We believe that the ethanol content alters the partition coefficients of the chlorophenolic derivatives between the aqueous phase and the headspace [37].…”

Section: Study Of the Sampling Conditionssupporting

confidence: 85%

Assessment of the matrix effect on the headspace solid‐phase microextraction (HS‐SPME) analysis of chlorophenols in wines

Insa¹,

Besalú²,

Salvadó³

et al. 2007

J of Separation Science

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In this paper, we propose a comparative study to check the matrix effect on the extraction of three chlorophenols, 2,4,6-trichlorophenol (TCP), 2,3,4,6-tetrachlorophenol and pentachlorophenol, direct precursors of 2,4,6-trichloroanisole, in synthetic and commercial wines (white and red wines). A rapid, simple and sensitive methodology based on solid-phase microextraction (SPME) and GC with electron capture detection (GC-ECD) and mass spectrometric detection (GC-MS) was developed and the variables affecting the extraction process (temperature, time and salt content) were examined employing a factorial design at two levels. Since GC-ECD does not allow the clear identification of target analytes in white wine, owing to overlapped interferences, GC-MS/MS was used for subsequent examinations. Calibration curves were constructed in synthetic, white and red wine. Significant differences between the slopes of synthetic and red wine, with the exception of TCP, were observed. Analytical parameters were evaluated and satisfactory results were obtained, showing the usefulness of the headspace SPME (HS-SPME) method for determining chlorophenolic compounds in wines.

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Section: Study Of the Sampling Conditionssupporting

confidence: 85%

Assessment of the matrix effect on the headspace solid‐phase microextraction (HS‐SPME) analysis of chlorophenols in wines

Insa¹,

Besalú²,

Salvadó³

et al. 2007

J of Separation Science

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“…Several kinds of SPME fibers are commercially available including polydimethylsiloxane (PDMS) [5][6][7][8][9][10][11], carbowax-divinlybenzene (CW-DVB) [12,13], polydimethylsiloxane-divinlybenzene (PDMS-DVB) [14][15][16], polyacrylate (PA) [17][18][19], divinylbenzene-carboxen-polydimethylsiloxane (DVB-CAR-PDMS) [20][21][22]. In recent years, studies have been focused on fabricating low cost, simple, robust and long-life fiber for the target analyte [23].…”

Section: Introductionmentioning

confidence: 99%

Preparation and characterization of sodium dodecyl sulfate doped polypyrrole solid phase micro extraction fiber and its application to endocrine disruptor pesticide analysis

Korba

Pelit

et al. 2013

Journal of Chromatography B

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“…So far, various analytical methods have been reported for determination of triadimefon residues in foods and environments, e.g., gas chromatography (GC) [5][6][7], gas chromatography-mass spectrometry (GC-MS) [8][9][10], liquid chromatography (LC) [11,12], and liquid chromatography-mass spectrometry (LC-MS) [13][14][15][16][17][18]. Furthermore, some studies focused on the chiral separation of triadimefon using capillary electrophoresis (CE) [19,20] and LC [21,22].…”

mentioning

confidence: 99%

A Validated LC Method for Determination of Trace Impurities in Technical Triadimefon

et al. 2011

Chromatographia

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A simple and sensitive liquid chromatography with ultraviolet detection (LC-UV) method was developed for the determination of three impurities with a content over 0.1% (w/w) in technical triadimefon. A Gemini C 18 column (5 lm, 250 mm 9 4.6 mm i.d.) was used for the chromatographic separations. The samples were separated by gradient elution with water (solvent A) and methanol (solvent B) using the following conditions: 70% A isocratic for 12 min, linear to 0% A within 8 min, and isocratic for 10 min at 0% A with a flow rate of 1.0 mL min -1 . Chromatograms were recorded at an absorption wavelength of 280 nm. The chromatographic resolutions between triadimefon and its potential impurities A, B, and C were greater than 3. The developed LC method was validated with respect to linearity, accuracy, precision, and robustness. This method was successfully applied to analyze the impurities in commercial technical triadimefon. In addition, the structures of the three impurities were identified to be (A) 4-chlorophenol, (B) 1-(2,4-dichlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone, and (C) 1,1-bis(4-chlorophenoxy)-3,3-dimethyl-2-butanone.

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Coupling solid-phase microextraction and high-performance liquid chromatography for direct and sensitive determination of halogenated fungicides in wine

Cited by 65 publications

References 28 publications

Assessment of the matrix effect on the headspace solid‐phase microextraction (HS‐SPME) analysis of chlorophenols in wines

Assessment of the matrix effect on the headspace solid‐phase microextraction (HS‐SPME) analysis of chlorophenols in wines

Preparation and characterization of sodium dodecyl sulfate doped polypyrrole solid phase micro extraction fiber and its application to endocrine disruptor pesticide analysis

A Validated LC Method for Determination of Trace Impurities in Technical Triadimefon

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