Could direct stenting reduce no-reflow in acute coronary syndromes? A randomized pilot study

Sabatier, Rémi; Hamon, Martial; Zhao, Quan; Burzotta, Francesco; Lecluse, E.; Valette, B; Grollier, Gilles

doi:10.1067/mhj.2002.122509

Cited by 30 publications

(27 citation statements)

References 20 publications

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“…The incidence of in-hospital major adverse cardiac was 4.1% after direct stent implantation and 11.5% after conventional stenting. This finding is consistent with several other studies, which could not demonstrate significant differences with respect to death, reinfarction or target vessel revascularization [15,20,21]. Antoninucci et al however found a significant lower mortality in patients who underwent DS [16].…”

Section: Discussionsupporting

confidence: 92%

“…There was a higher incidence of no-reflow in the CS group after (CS 9% vs. DS 4%, n.s. ), but this difference was statistically not significant and is comparable to the results of several other studies [16,20]. Contrary to our results Atamaca et al found a significant difference between the two techniques according to the rate of no-reflow, which may be explained by the fact that glycoprotein IIb/IIIa inhibitors were not used in their study [21].…”

Section: Discussioncontrasting

confidence: 85%

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Direct versus conventional stent implantation in patients with acute coronary syndrome just before the era of drug-eluting stents

Süselbeck

Türkoglu

Lang

et al. 2005

International Journal of Cardiology

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Section: Discussionsupporting

confidence: 92%

Section: Discussioncontrasting

confidence: 85%

Direct versus conventional stent implantation in patients with acute coronary syndrome just before the era of drug-eluting stents

Süselbeck

Türkoglu

Lang

et al. 2005

International Journal of Cardiology

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“…DS is commonly used in acute coronary syndromes with few angiographically calcified lesions. In contrast, CS is typically used in stable angina, in elderly patients and/or for strongly calcified lesions (14,15). The inflammatory potential of such lesions differs between soft and strong lesions.…”

mentioning

confidence: 93%

Percutaneous coronary intervention-induced variations in systemic parameters of inflammation: relationship with the mode of stenting

Brasselet¹,

Garnotel²,

Perotin³

et al. 2007

Clinical Chemical Laboratory Medicine

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“…However, distal embolization and no-reflow still might cause a problem. Direct stent implantation does not bring any improvement to PTCA in the prevention of distal embolization (12,13). Inadequate epicardial blood flow and noreflow may lead to left ventricular remodeling.…”

Section: Discussionmentioning

confidence: 99%

Effects of Percutaneous Coronary Thrombectomywith the X-Sizer Catheter on Epicardial Flow and Microvascular Function in Acute Coronary Syndromes

Bilge

Nişancí

Yılmaz

et al. 2005

Clin Appl Thromb Hemost

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During percutaneous coronary intervention, slow coronary flow and distal embolization are still important problems, especially in cases with intracoronary thrombus. The aim of this study was to learn the effectiveness and early term results of thrombectomy with the X-SIZER catheter system in acute coronary syndrome. Twenty-nine patients (22 [76%] men; 55.9 +/- 11.1 years) with acute coronary syndrome and intracoronary thrombus detected in coronary angiography were included into the study. X-sizer thrombectomy was applied to 14 of the patients, and conventional percutaneous transluminal coronary angioplasty (PTCA) was applied to the others. Baseline characteristics were similar in both groups. Mean thrombolysis in myocardial infarction (TIMI) flow increased from 0.8 +/- 0.9 to 2.4 +/- 0.6 in X-sizer-treated patients (p<0.001) and TIMI 3 flow was maintained in 71.4% of the patients. Similary, mean TIMI flow increased from 0.36 +/- 0.81 to 2.73 +/- 0.47 in conventional PTCA-treated patients (p<0.001) and TIMI 3 flow was maintained in 73% of the patients (NS). Mean myocardial blush grade (MBG) increased from 0.7 +/- 0.7 to 2.6 +/- 0.6 in X-sizer-treated patients (p<0.001) and from 0.27 +/- 0.65 to 2.36 +/- 0.67 in the conventional PTCA-treated patients (p<0.001). Postprocedural MBG 3 was obtained in 64.3% of X-Sizer-treated patients and in 45% of controls. Although microvascular function in the thrombectomy-applied patients was found better, there was no significant difference between the two groups. Furthermore it was detected that the use of tirofiban yielded no additional improvement in epicardial and microvascular flow. In acute coronary syndromes, use of X-sizer in addition to primary percutaneous coronary interventions is a safe and relatively effective method in the prevention of distal embolization.

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Could direct stenting reduce no-reflow in acute coronary syndromes? A randomized pilot study

Cited by 30 publications

References 20 publications

Direct versus conventional stent implantation in patients with acute coronary syndrome just before the era of drug-eluting stents

Direct versus conventional stent implantation in patients with acute coronary syndrome just before the era of drug-eluting stents

Percutaneous coronary intervention-induced variations in systemic parameters of inflammation: relationship with the mode of stenting

Effects of Percutaneous Coronary Thrombectomywith the X-Sizer Catheter on Epicardial Flow and Microvascular Function in Acute Coronary Syndromes

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