Costs of Illness Due to Bordetella pertussis in Families

Lee, Lucia H.; Pichichero, Michael E.

doi:10.1001/archfami.9.10.989

Cited by 64 publications

(41 citation statements)

References 26 publications

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“…en 2000, estimó que los costos médicos directos de la BP se encontraban en 2822 dólares para los menores de 2 años, en los cuales la internación representó el 75% del costo total. 30 O ' B r i e n ( 2 0 0 5 ) , e n u n a m u e s t r a m á s representativa de la población del mismo país, calculó para los menores de un año un costo de 9580 dólares. 31 En nuestro estudio, los costos médicos directos asociados a la hospitalización constituyeron el 96% del costo total.…”

Section: Tabla 4 Costos Indirectos Y Gastos De Bolsillounclassified

Costos de la enfermedad por Bordetella pertussis en hospitales terciarios de la Argentina

et al. 2013

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Section: Tabla 4 Costos Indirectos Y Gastos De Bolsillounclassified

Costos de la enfermedad por Bordetella pertussis en hospitales terciarios de la Argentina

et al. 2013

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“…28 BP cost studies are rare in Latin America, but they are available in North America [29][30][31] and Europe. 32,33 Most of them highlight that the estimations of BP direct medical costs depend on age: they are higher in infants younger than 1 year old because this age group usually requires hospitalization, as mentioned above.…”

Section: Resource and Unit Mean And Sd Median Costs (Mean And Sd) Cosmentioning

confidence: 99%

“…The study conducted in the USA by Lee, et al in 2000 estimated that BP direct medical costs were 2822 USD for children younger than 2 years old, and in this group, hospitalization accounted for 75% of the total cost. 30 O'Brien (2005) had a more representative population sample and estimated that for infants younger than 1 year old, the cost amounted to 9580 USD. 31 In our study, hospitalization-related direct medical costs accounted for 96% of total costs.…”

Section: Resource and Unit Mean And Sd Median Costs (Mean And Sd) Cosmentioning

confidence: 99%

“…It is believed that hospitalization of adolescents and adults with whooping cough is infrequent; however, some studies have documented that up to 7.5% of 10-19 year old individuals and 5.7% of >20 year old individuals with whooping cough do require hospitalization. 29,30 No reliable data are available in Argentina regarding this aspect.…”

Section: Resource and Unit Mean And Sd Median Costs (Mean And Sd) Cosmentioning

confidence: 99%

“…32 In our study, the average stay in the internal medicine unit was 6.5 days, and results are similar to those observed by Lee, et al and O'Brien in infants younger than 1 years old in the USA. 30,31 Direct non-medical costs and overhead costs are only 4% of total costs, and correspond to 419.91 ARS (84 USD) per family, approximately 8% of an average salary (5194 ARS for the third quarter of 2011, according to INDEC, the Statistics and Censuses Institute of Argentina). 34 In the study by Rowensztein, et al 35 on respiratory disease costs in 2004, the total transportation expenses were 41.92 ARS (8 USD).…”

Section: Resource and Unit Mean And Sd Median Costs (Mean And Sd) Cosmentioning

confidence: 99%

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Cost of Bordetella pertussis illness in tertiary hospitals in Argentina

Gentile¹

2013

Arch Argent Pediat

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The National Immunization Commission and the National Program for the Control of Vaccine-Preventable Diseases (Programa Nacional de Control de Enfermedades Inmunoprevenibles, ProNaCEI) updated the immunization policy in relation to Bordetella pertussis (BP) in 2009 in order to improve the control of this disease in accordance with international recommendations. To evaluate the financial impact of this new immunization policy, we must first know the cost on the health system of having a hospitalized or outpatient child infected with BP. The objective of this study was to describe the profile of costs of hospitalized or outpatient children with laboratory-confirmed BP infection in three hospitals of Argentina. This was a prospective study of the cost of BP in the period between December 2010 and March 2012. Results. The total cost for the entire cohort was 1 170 663.32 ARS (236 497.64 USD); direct medical costs were 1 124 052.31 ARS (227 081.27 USD); indirect costs and out-of-pocket expenses were 46 611 ARS (9416.6 USD). From this data, it is possible to conclude that the total average cost per patient was 10 546.52 ARS (95% CI: 9009-13 840) (2130.60 USD, 95% CI: 1820-2795), the direct medical cost per patient was 10 126.6 ARS (95% CI: 8607-13 171) (2045.77 USD, 95% CI: 1738-2660), and the indirect plus out-of-pocket costs (transportation and extras) were 419.92 ARS (95% CI: 344.7-565.3) (84 USD, 95% CI: 69-115). Conclusion. The cost of a hospitalized child with confirmed BP is 10 546.52 ARS (95% CI: 9009-13 840) (2130.60 USD, 95% CI: 1820-2795). Direct non-medical costs and overhead costs account for 4% of the total cost, amounting to 419.91 ARS per family (84 USD, 95% CI: 69-115), approximately an 8% of an average salary.

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Pertussis Immunisation in Adolescents and Adults

Heininger

2008

Advances in Experimental Medicine and Biology

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The burden of disease in affected adolescents and adults, their important contribution to the ongoing circulation of B. pertussis in the population, and the associated direct and indirect costs make prevention of pertussis by immunisation beyond childhood an attractive goal. The recent introduction of booster doses in adolescents in Austria, Australia, Canada, France, Germany, and the United States are an important step in the right direction. However, this most likely will not have a significant impact on reduction of disease in young infants and adults. It will be a challenge for the next few years to convince authorities, health care providers, and the general population about the necessity of regular pertussis vaccine booster doses in adults if better control of this potentially devastating disease is wanted. Although, as has recently been said (Cherry 2005), this "may be looked on by many as a pie-in-the-sky vision," the availability of tetanus toxoid, reduced diphtheria toxoid, and reduced acellular pertussis, adsorbed (Tdap) vaccines with proven tolerability and immunogenicity make this goal achievable. Introduction and enforcement of regular pertussis boosters, e.g. every 10 years, will not only reduce the overall morbidity of pertussis in the population but most likely--by use of combination vaccines--will also improve the less than optimal coverage of diphtheria and tetanus immunisations in adults.

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Costs of Illness Due to Bordetella pertussis in Families

Abstract: The adverse financial effect of pertussis on 69 families in Monroe County, New York, was $145,903 ($2115 per family) and supports the need for booster immunizations in adolescents and adults. Arch Fam Med. 2000;9:989-996

Cited by 64 publications

References 26 publications

Costos de la enfermedad por Bordetella pertussis en hospitales terciarios de la Argentina

Costos de la enfermedad por Bordetella pertussis en hospitales terciarios de la Argentina

Cost of Bordetella pertussis illness in tertiary hospitals in Argentina

Pertussis Immunisation in Adolescents and Adults

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