Cost-effectiveness of two-dose human papillomavirus vaccination in Singapore

Abstract

Introduction: Cervical cancer is the tenth most common cancer and the eighth most frequent

Clinical and economic impact of school‐based nonavalent human papillomavirus vaccine on women in Singapore: a transmission dynamic mathematical model analysis

“…The long‐term impact of mass HPV vaccination is enormous. As yet, there is no school‐based HPV vaccination in Singapore despite previous studies showing that school‐based HPV vaccination is cost‐effective for both quadrivalent and bivalent HPV vaccines . Nonavalent HPV vaccine extends the protection of quadrivalent vaccine to HPV 31/33/45/52/58 infection and related CIN and cervical cancer.…”

“…As yet, there is no school-based HPV vaccination in Singapore despite previous studies showing that school-based HPV vaccination is cost-effective for both quadrivalent and bivalent HPV vaccines. 28,29,34 Nonavalent HPV vaccine extends the protection of quadrivalent vaccine to HPV 31/33/45/52/58 infection and related CIN and cervical cancer. It also adds to the bivalent vaccine, the protection of HPV 6/11 infection and related CIN1 and genital warts in women and men.…”

Landscape of vaccine access and health technology assessment role in decision-making process in ASEAN countries

“…72 Several economic evaluation studies for HPV immunization were conducted in Lao PDR, Indonesia, Malaysia, Singapore, Thailand, and Vietnam and most found that the vaccine is a very cost-effective strategy. 69,[73][74][75][76][77] Dengue vaccine (DV)…”