Cost-effectiveness of postmastectomy hypofractionated radiation therapy vs conventional fractionated radiation therapy for high-risk breast cancer

Abstract

postmastectomy hypofractionated radiation therapy vs conventional fractionated radiation therapy for high-risk breast cancer, The Breast,

Cost-effectiveness of Post-Mastectomy Radiotherapy (PMRT) for breast cancer in India: An economic modelling study

“…These findings are like other studies which demonstrate a QALY gain ranging from 0.19 to 0.76. 10 , 12 , 13 , 39 In terms of ICER, our findings are consistent with other studies in different settings. Wan et al reports that PMRT for patients with 1–3 node involvement is cost-effective in China, however, uncertainty of PMRT being cost-effective are relatively greater for patients with pN4+.…”

Comparing Hypofractionated With Conventional Fractionated Radiotherapy After Breast-Conserving Surgery for Early Breast Cancer: A Meta-Analysis of Randomized Controlled Trials

“…A study from the USA reported that HFRT could save the US healthcare system millions of dollars in healthcare costs if it follows evidence-based practice guidelines and if expert advice is chosen appropriately (63). In addition, despite population differences, recent studies have demonstrated for the first time that post-mastectomy HFRT is often more cost-effective than CFRT for women at high risk of breast cancer in China, France, and the United States (64).…”

Benefits of Adopting Hypofractionated Radiotherapy as a Standard of Care in Low-and Middle-Income Countries

“…31 A study on the cost effectiveness of hypofractionated compared with conventionally fractionated postmastectomy breast radiation in China found that it was associated with an 11% cost reduction and was determined to be cost-effective. 54 Another study from China reported that neoadjuvant 10-fraction hypofractionated radiation for esophageal cancer resulted in a 41% reduction in radiotherapy costs over a 20-fraction moderately hypofractionated regimen. 53 Reducing the treatment costs patients incur is equally important to reducing the costs for the overall health care system.…”