Cosmetics use and age at menopause: is there a connection?

Abstract

Short Narrative Abstract Cosmetics contain a vast number of chemicals, most of which are not under the regulatory purview of the Food and Drug Administration. Only a few of these chemicals have been evaluated for potential deleterious health impact – parabens, phthalates, polycyclic aromatic hydrocarbons, and siloxanes. A review of the ingredients in the best-selling and top rated products of the top beauty brands in the world, as well as a review of highlighted chemicals by non-profit environmental organizations reveal 11 chemicals and chemical families of concern: butylated hydroxyanisole/butylated hydroxytoluene, coal tar dyes, diethanolamine, formaldehyde releasing preservatives, parabens, phthalates, 1,4 dioxane, polycyclic aromatic hydrocarbons, siloxanes, talc/asbestos, and triclosan. Age at menopause can be affected by a variety of mechanisms, including endocrine disruption, failure of DNA repair, oxidative stress, shortened telomere length, and ovarian toxicity. There is a lack of available studies to make a conclusion regarding cosmetics use and age at menopause. What little data there is suggests future studies are warranted. Women with chronic and consistent use of cosmetics across their lifespan may be a population of concern. More research is required to better elucidate the relationship and time windows of vulnerability and the effects of mixtures and combinations of products on ovarian health.

Racial/Ethnic Disparities in Pregnancy and Prenatal Exposure to Endocrine-Disrupting Chemicals Commonly Used in Personal Care Products

“…As such, we conducted a scoping review to understand the current state of the literature on racial/ ethnic differences in chemical exposures occurring during pregnancy and the prenatal period that are linked to potentially modifiable risk factors. For this, we summarized the literature that examines pregnancy and prenatal exposure to 8 chemicals or classes of chemicals previously identified as chemicals of concern found in PCPs (phthalates, parabens, benzophenone-3, triclosan, cyclic volatile methylsiloxanes, formaldehydereleasing preservatives, 1,4-dioxane, and diethanolamine) [35][36][37] among women of different racial/ethnic backgrounds in the contiguous US and Puerto Rico. We also reviewed articles that report stratified data on pregnancy and prenatal exposure to the 8 chemicals or classes of concern, but do not examine the racial/ethnic disparities in exposure.…”

The environmental injustice of beauty: framing chemical exposures from beauty products as a health disparities concern

“…6, 9, 10 Exposure to one or more of these chemicals has been linked to endocrine disruption, cancer, reproductive harm and impaired neurodevelopment in children. 11–14 Women ages 18 to 34 are more likely to be “heavy buyers”, purchasing more than ten types of products a year.…”

“…Consumer products, and personal care products specifically, are a source of exposure to toxic chemicals for all women. 6–8 Beauty products (one category of personal care products) have limited and inconsistent disclosure of chemical ingredients and most lack adequate data on health and safety. 6, 9 …”

Formulasi dan Uji Kecerahan Ekstrak Krim Lulur Daun Kelor (Moringa oleifera) Sebagai Pemutih Kulit Pada Tikus Putih (Rattus norvegicus)

“…Kosmetik saat ini mengandung sejumlah besar bahan kimia dan sebagian besar tidak mengikuti peraturan administrasi yang diatur pada makanan dan obat obatan, sebagian kecil telah dievaluasi potensi merugikan bagi kesehatan(Erika Chow & Mahalingaiah, 2017) . saat ini orang lebih mengarah pada pengobatan alami, untuk kosmetik herbal kosmetik lebih alami karena dibuat dari herba maupun ekstrak tanaman.…”