Cosmetic Potential of Natural Products: Industrial Applications

Krishna, Mahesh S.; Jaseela, Fathima; Girija, Veena Vijayan

doi:10.1007/978-981-13-7205-6_10

Cited by 36 publications

(30 citation statements)

References 134 publications

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“…For instance, between 1981 and 2014 over 50% of newly developed drugs were developed from NPs [1]. NPs and their derivatives are also actively studied in food [4][5][6][7][8], cosmetic industries [9,10] and in agriculture, with natural pesticides development [11]. This growing interest over NPs and their application resolved in uncontrollable growth of the number of published open and commercial databases, industrial catalogues, books of NPs and collections of structures provided in supplementary materials or research articles, compiling NPs from various organisms, geographical locations, targeted diseases and traditional uses.…”

Section: Introductionmentioning

confidence: 99%

Review on natural products databases: where to find data in 2020

2020

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Natural products (NPs) have been the centre of attention of the scientific community in the last decencies and the interest around them continues to grow incessantly. As a consequence, in the last 20 years, there was a rapid multiplication of various databases and collections as generalistic or thematic resources for NP information. In this review, we establish a complete overview of these resources, and the numbers are overwhelming: over 120 different NP databases and collections were published and re-used since 2000. 98 of them are still somehow accessible and only 50 are open access. The latter include not only databases but also big collections of NPs published as supplementary material in scientific publications and collections that were backed up in the ZINC database for commercially-available compounds. Some databases, even published relatively recently are already not accessible anymore, which leads to a dramatic loss of data on NPs. The data sources are presented in this manuscript, together with the comparison of the content of open ones. With this review, we also compiled the open-access natural compounds in one single dataset a COlleCtion of Open NatUral producTs (COCONUT), which is available on Zenodo and contains structures and sparse annotations for over 400,000 non-redundant NPs, which makes it the biggest open collection of NPs available to this date.

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Section: Introductionmentioning

confidence: 99%

Review on natural products databases: where to find data in 2020

2020

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“…The cosmetic industry is a multibillion dollar-level industry with increasing research every year. Natural products isolated from plant and animal resources are potential active cosmetic candidates for treating various skin disorders and inflammation and protection against UV irradiation [ 2 ]. Excessive solar exposure, such as that to UVB radiation, is toxic to the skin, inducing skin aging, DNA skin damage, and tumorigenesis.…”

Section: Introductionmentioning

confidence: 99%

Low Molecular Weight Oligosaccharide from Panax ginseng C.A. Meyer against UV-Mediated Apoptosis and Inhibits Tyrosinase Activity In Vitro and In Vivo

Dai

Yang

Song

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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To find new anti-UV and whitening agents, 21 fractions isolated from three preparations of ginseng (white, red, and black ginseng) were screened, and their antioxidant effects on AAPH- or H2O2-induced damage were investigated. Furthermore, the protective effect against UV-mediated apoptosis and the tyrosinase inhibitory activity of the targeted fractions were evaluated in vitro and in a zebrafish model. Among all fractions, F10 from white ginseng was selected as having the strongest anti-UV and antimelanogenesis activities. This fraction exhibited excellent inhibitory effects on the pigmentation of zebrafish, which may be due to its potential tyrosinase inhibitory activity. Additionally, the chemical composition of F10 was evaluated by UPLC-MS and NMR instruments. The results indicated that F10 had a carbohydrate content of more than 76%, and the weight-average molecular weight was approximately 239 Da. Disaccharide sucrose was the main active compound in F10. These results suggest that F10 could be used as an ingredient for whitening cosmetics and regarded as an anti-UV filter in the future.

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“…Therefore, there is an undeniable need to find safer, eco-friendly and upgraded alternatives to serve as new ingredients for sunscreen improvement. In this regard, natural products constitute an essential opportunity to discover compounds with engaging biological activities for both pharmaceutical and cosmetic industries [ 25 , 26 ]. Despite such promising chemical and biological traits, research on compounds of natural origin has several significant logistical and technological disadvantages that limit their industrial application, such as the naturally occurring complex structures (expensive and time-consuming to synthesize) [ 27 ], low yield during the isolation process and limited availability of source organisms to yield higher amounts to satisfy supply [ 28 , 29 ].…”

Section: Introductionmentioning

confidence: 99%

Streptomyces-Derived Metabolites with Potential Photoprotective Properties—A Systematic Literature Review and Meta-Analysis on the Reported Chemodiversity

et al. 2020

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Sun overexposure is associated with the development of diseases that primarily affect the skin, which can lead to skin cancer. Among the main measures of photoprotection is the use of sunscreens. However, there is currently concern about the reported harmful effects to both humans and the environment due to several of the sunscreen ingredients available on the market. For this reason, the search for and development of new agents with photoprotective properties is required. In searching for these metabolites, researchers have turned their attention to microbial sources, especially the microbiota in unusual hostile environments. Among the diverse microorganisms available in nature, Actinobacteria and specifically Streptomyces, have been shown to be a source of metabolites with various biological activities of interest, such as antimicrobial, antitumor and immunomodulator activities. Herein, we present the results of a systematic review of the literature in which Streptomyces isolates were studied as a source of compounds with photoprotective properties. A meta-analysis of the structure-property and structure-activity relationships of those metabolites identified in the qualitative analysis phase was also carried out. These findings indicate that Streptomyces are a source of metabolites with potential applications in the development of new, safe and more eco-friendly sunscreens.

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Cosmetic Potential of Natural Products: Industrial Applications

Cited by 36 publications

References 134 publications

Review on natural products databases: where to find data in 2020

Review on natural products databases: where to find data in 2020

Low Molecular Weight Oligosaccharide from Panax ginseng C.A. Meyer against UV-Mediated Apoptosis and Inhibits Tyrosinase Activity In Vitro and In Vivo

Streptomyces-Derived Metabolites with Potential Photoprotective Properties—A Systematic Literature Review and Meta-Analysis on the Reported Chemodiversity

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