Cosmetic Plants in Nigeria

Bever, Bep Oliver

doi:10.3109/13880206709083330

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1992

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“…It is a widely used local plant in Nigeria for both therapeutic and nutritional purposes. In addition to its numerous uses in folklore (Dalziel, 1937;Bever, 1960), the leaf decoction of the plant is traditionally employed as an antidiabetic remedy. The present study was stimulated by the observation that a diabetic patient in one of our medical centres who was unresponsive to insulin therapy showed a remarkable improvement after taking 'bitter leaf' soup (data not shown).…”

Section: Introductionmentioning

confidence: 99%

Blood sugar lowering effect of Vernonia amygdalina Del, in an experimental rabbit model

Akah

Okafor

1992

Phytotherapy Research

148

112

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The aqueous leaf extract of Vernonia amygdalinu, Del, (Compositae) given i.p. produced a dose-related fall in blood sugar. A dose of 80 mg/kg body weight of adult rabbit produced a maximum lowering of blood sugar in both fasted normal and alloxanized rabbits. The fasting blood sugar in normoglycaemic rabbits w-as reduced from 96 mg% to 48 mg% in 4 h. In alloxanized rabbits, the blood sugar was reduced from the mean value of 520 mg% to 300 mg% in 8 h. The hypoglycaemic effects were compared with those of tolbutamide. Acute toxicity studies of the extract in mice gave LDso value of 1122mg/kg body weight when given i.p. The blood sugar lowering effect of Vernonia amygdalina extract may involve a mechanism not related to insulin secretion.

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Section: Introductionmentioning

confidence: 99%