Corynebacterium accolens sp. nov., a Gram-Positive Rod Exhibiting Satellitism, from Clinical Material

The Family Corynebacteriaceae

“…The evolutionary event of gene loss occurred independently in distinct phyletic lines within the phylogenetic tree of the family Corynebacteriaceae ( > Fig. 12.1) and probably includes not only the hitherto examined species Corynebacterium bovis (Funke et al 1997b), Corynebacterium jeikeium (Jackman et al 1987), Corynebacterium kroppenstedtii , Corynebacterium resistens (Otsuka et al 2005), and Corynebacterium urealyticum (Pitcher et al 1992) but also the other known lipophilic species Corynebacterium accolens (Neubauer et al 1991), Corynebacterium afermentans subsp. lipophilum (Riegel et al 1993a), Corynebacterium appendicis (Yassin et al 2002a), Corynebacterium aquatimens (Aravena-Román et al 2012), Corynebacterium lipophiloflavum (Funke et al 1997c), Corynebacterium macginleyi (Riegel et al 1995b), Corynebacterium mastitidis (Fernández-Garayzábal et al 1997), Corynebacterium pyruviciproducens (Tong et al 2010), Corynebacterium sputi (Yassin and Siering 2008), Corynebacterium tuberculostearicum (Feurer et al 2004), and Corynebacterium ureicelerivorans (Yassin 2007).…”

“…The genomic G+C content of Corynebacterium accolens isolates varies between 53.9 and 63.2 mol%, indicating that the characterized collection of strains contains various genomospecies (Neubauer et al 1991).…”

“…Many of the medically relevant Corynebacterium species can also be recovered as commensals or contaminants from a variety of clinical specimens (Bernard 2012). Species associated with humans in addition to Corynebacterium diphtheriae include the following: Corynebacterium accolens from various clinical materials isolated from both patients and healthy individuals, a breast abscess, a case of endocarditis of native aortic and mitral valves, and the anterior nares (Neubauer et al 1991;Claeys et al 1996; Ang and Brown 2007; The Human Microbiome Project Consortium 2012b); Corynebacterium afermentans from blood cultures and multiple abscesses in brain, lung, and liver (Riegel et al 1993a;Dykhuizen et al 1995;Minkin and Shapiro 2004); Corynebacterium ammoniagenes from infant feces and floor dust samples (Collins 1987b;Täubel et al 2009); Corynebacterium amycolatum from human skin, clinical specimens, and female patients with mastitis (Collins et al 1988a;Lagrou et al 1998;Paviour et al 2002); Corynebacterium appendicis from an abdominal swab of a patient with appendicitis accompanied with abscess formation (Yassin et al 2002a); Corynebacterium aquatimens from blood cultures of a patient with bacteremia (Aravena-Román et al 2012); Corynebacterium argentoratense from human throat specimens (Riegel et al 1995d); Corynebacterium atypicum from an unknown human clinical source (Hall et al 2003); Corynebacterium aurimucosum from various clinical sources and in samples from the female urogenital tract (Yassin et al 2002b;Daneshvar et al 2004); Corynebacterium auris from patients with ear infections (Funke et al 1995a); Corynebacterium confusum from a blood culture, patients with foot infections, and a breast abscess (Funke et al 1998a;Bernard et al 2002); Corynebacterium coyleae from blood cultures of patients with previous surgical intervention and a pancreatic abscess (Funke et al 1997a;Taguchi et al 2006); Corynebacterium durum from respiratory tract specimens, sputum, and a neck abscess (Riegel et al 1997b;von Graevenitz et al 1998;Bernard et al 2002); Corynebacterium falsenii from blood cultures and a clinically significant bacteremia oc...…”

Corynebacterium accolens -Associated Pelvic Osteomyelitis

“…Corynebacterium accolens (previously CDC Corynebacterium group G-1) was first described by Neubauer et al in 1991 (7,11). It is a Gram-positive bacillus considered to be an inhabitant of the upper respiratory tract.…”

“…It is a Gram-positive bacillus considered to be an inhabitant of the upper respiratory tract. It has been isolated from human clinical specimens from sites including wound drainage, endocervix, sputum, throat swab, breast abscess, and valvular vegetations (1,4,7,8,11). It has also been isolated from cases of sepsis, otitis media, keratoconjunctivitis, sinusitis maxillaris, and meningitis (4,11).…”