The Family Corynebacteriaceae

Colonization of human epithelial cell lines by Corynebacterium ulcerans from human and animal sources

“…Corynebacterium ulcerans is a pathogenic member of the genus Corynebacterium, which is part of the family Corynebacteriaceae, the order Actinomycetales and the phylum Actinobacteria (Tauch & Sandbote, 2014). Within the phylum Actinobacteria, the genera Corynebacterium, Nocardia and Mycobacterium form a monophyletic branch, the CMN group, based on their unusual cell envelope composition (Burkovski, 2013).…”

A microbiological and clinical review on Corynebacterium kroppenstedtii

“…Most Corynebacterium species contain mycolic acids with 22 -36 carbons, although ranges of 20 À 38 carbons have also been detected. 2 Species lacking mycolic acids are Corynebacterium amycolatum, Corynebacterium caspium, Corynebacterium ciconiae, Corynebacterium lactis, and C. kroppenstedtii. 9,13,14 According to genome sequence data, the lack of mycolic acids in C. kroppenstedtii may be caused by gene loss, comprising at least a condensase gene region and a mycolate reductase gene, both contributing to the biosynthesis of mycolic acids in other corynebacteria.…”

“…15 The phylogenetic relationship of C. kroppenstedtii with other Corynebacterium species can be deduced from dendrograms that generally derive from the alignment of the 16S rRNA or rpoB gene sequences. 2,16,17 The rpoB gene sequence of corynebacteria allows accurate species identification, as it is significantly more polymorphic than the 16S rRNA gene. Phylogenetic analysis on the basis of rpoB gene sequence alignment has revealed four clusters in the genus Corynebacterium with a reliable taxonomic organization supported by high bootstrap values.…”

“…1 Some Corynebacterium species are serious pathogens of humans or animals, whereas others are useful in industrial applications and in food production. 2 The detection of corynebacteria in various habitats of the human body has broadened in recent years as a result of culture-independent approaches and the application of next-generation DNA sequencing technologies. 3,4 These studies have provided vast sets of 16S rRNA gene sequences, and through this, a compilation of the bacterial repertoire that is associated with human beings as commensals or pathogens.…”

Corynebacterium pseudodiphtheriticum: Putative probiotic, opportunistic infector, emerging pathogen

“…A few species have been found in humans and animals, implicating a putative zoonotic transmission pathway to humans. 1 Within the group of medically relevant corynebacteria only a very limited number of Corynebacterium species are potent human pathogens, such as Corynebacterium diphtheriae, the etiological agent of diphtheria 2,3 , while many species are rare causes of infections.…”