Abstract:479ing resistance to infection. Because these small doses were shown to be non-toxic to the normal animal, it would seem that cortisone has some specific detrimental effect in mouse typhoid.Summary. Cortisone, administered in single injections ranging from 0.25 to 5 mg, markedly decreased resistance of mice to S. typhimurium. Cortisone had the greatest effect on resistance when administered within 2 days before or after typhoid inoculation. Subcutaneous injections of two other steroids, progesterone and deso'x… Show more
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