“…It is well known that exogenous corticosteroids depress adrenal cortical function (Shuster and Williams, 1961;Treadwell et al, 1963), and there is some evidence that adrenocortical suppression occurs in asthmatic children receiving low doses of corticosteroids (Kerrebijn, de Kroon, and Harders, 1967). The present investigation was undertaken to determine to what extent children on long-term corticosteroid therapy were subject to suppression of adrenal cortical function, and if possible to relate this to the amounts of steroid administered, as Wood et al (1965) have done for the adult.…”