Kuzemko, J. A., and Lines, J. G. (1971). Archives of Disease in Childhood, 46, 366. Adrenal cortical function in asthmatic children on alternate-day steroids. Adrenal cortical function was determined in 16 children receiving prednisolone or prednisolone stearoylglycolate on alternate days. The dosages of the corticosteroids varied from 2-5 to 10 mg prednisolone, or 6 65 to 13-30 mg of its stearoylglycolate ester; the duration of therapy ranged from 2 to 26 months. Adrenocortical function was assessed from the plasma cortisol response to a single injection of l1-24 tetracosactrin (Synacthen); repeat tests were performed after altering steroid dosages or for reassessment of individual patients. The effects of prednisolone stearoylglycolate are compared with those of prednisolone, and the effects of alternate-day prednisolone therapy are compared with those found when this corticosteroid was given daily to similar (in three cases, the same) children.