Cortical calcification in sturge–weber syndrome on MRI‐SWI: Relation to brain perfusion status and seizure severity

Wu, Jianlin; Tarabishy, Bisher; Hu, Jiani; Miao, Yanwei; Cai, Zhaocheng; Xuan, Yang; Behen, Michael E.; Li, Meng; Ye, Yongquan; Shoskey, Richard; Haacke, E. Mark; Juhász, Csaba

doi:10.1002/jmri.22687

Cited by 60 publications

(52 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Given the abnormal leptomeningeal venous system and impaired cortical venous outflow, these patients have prominent transmedullary venous channels that are best detected by SWI and can mimic DVA (Fig ). Additional imaging findings in SWS can include focal cortical anomalies and atrophy, leptomeningeal enhancement, and cortical calcification …”

Section: Anomalies Associated With Dva and Imaging Mimicsmentioning

confidence: 99%

The Many Faces of Cerebral Developmental Venous Anomaly and Its Mimicks: Spectrum of Imaging Findings

Nabavizadeh

Mamourian

Vossough

et al. 2016

Journal of Neuroimaging

View full text Add to dashboard Cite

Developmental venous anomalies (DVAs) are the most common cerebral vascular malformations and are usually found incidentally on neuroimaging studies. Despite the benign nature of DVAs, occasionally, they can be symptomatic. The objective of this article is to review the spectrum of imaging findings of DVAs on conventional and advanced imaging studies. In addition, neuroimaging findings of symptomatic DVAs as well as imaging mimicks will also be described to assist in the approach to differential diagnosis.

show abstract

Section: Anomalies Associated With Dva and Imaging Mimicsmentioning

confidence: 99%

The Many Faces of Cerebral Developmental Venous Anomaly and Its Mimicks: Spectrum of Imaging Findings

Nabavizadeh

Mamourian

Vossough

et al. 2016

Journal of Neuroimaging

View full text Add to dashboard Cite

show abstract

“…9), 53 and low-flow VMs, including CCM, 20,23,88 brain capillary telangiectasia, 28 or Sturge-Weber syndrome. 48,110 Most importantly, the findings from SWI, especially at ultrahigh fields (that is, 7 T), 29 are shown to correlate with histopathological studies. 88 SWI is a promising technique since its findings correlate well with "gold-standard" techniques for detecting VMs, including digital subtraction angiography and time-of-flight MRA.…”

Section: Monitoring Outcome In Strokementioning

confidence: 90%

Magnetic resonance susceptibility weighted imaging in neurosurgery: current applications and future perspectives

Ieva¹,

Lam²,

Alcaide‐Leon

et al. 2015

JNS

View full text Add to dashboard Cite

T he initial development of MR venography by Reichenbach et al. 90 laid the foundation for Haacke et al. 42 to apply the principles of MR venography in conventional MRI for broader usage in clinical and research settings. By utilizing magnitude and phase information, both of which are normally acquired from conventional MRI data, susceptibility weighted imaging (SWI) has an enhanced ability to detect microhemorrhages 4,12,26 and microvasculature. 26,27,41,92 It is a highly sensitive imaging modality able to depict magnetic substances, such as deoxygenated hemoglobin, with high contrast 42 and to help investigate neurological diseases, 82 grade tumors, 25,63 and assist in determining treatment or prognosis. 18,26,37,70,71,115 Over the past years, the SWI technique has found applications in the different fields of neurosurgery, namely neurooncology, vascular neurosurgery, neurotraumatolabbreviatioNs AVM = arteriovenous malformation; CCM = cerebral cavernous malformation; CMB = cerebral microbleed; CVS = cortical vessel sign; DAI = diffuse axonal injury; DBS = deep brain stimulation; DWI = diffusion-weighted imaging; GBM = glioblastoma multiforme; GCS = Glasgow Coma Scale; GPe = external globus pallidus; GPi = internal GP; GRE = gradient-recalled echo; ITSS = intratumoral susceptibility signal; mIP = minimum intensity projection; MRA = MR angiography; MS = multiple sclerosis; PD = proton density; PQ = percentagewise quantification; PWI = perfusion-weighted imaging; SN = substantia nigra; STN = subthalamic nucleus; SWI = susceptibility weighted imaging; TBI = traumatic brain injury; VM = vascular malformation. Susceptibility weighted imaging (SWI) is a relatively new imaging technique. Its high sensitivity to hemorrhagic components and ability to depict microvasculature by means of susceptibility effects within the veins allow for the accurate detection, grading, and monitoring of brain tumors. This imaging modality can also detect changes in blood flow to monitor stroke recovery and reveal specific subtypes of vascular malformations. In addition, small punctate lesions can be demonstrated with SWI, suggesting diffuse axonal injury, and the location of these lesions can help predict neurological outcome in patients. This imaging technique is also beneficial for applications in functional neurosurgery given its ability to clearly depict and differentiate deep midbrain nuclei and close submillimeter veins, both of which are necessary for presurgical planning of deep brain stimulation. By exploiting the magnetic susceptibilities of substances within the body, such as deoxyhemoglobin, calcium, and iron, SWI can clearly visualize the vasculature and hemorrhagic components even without the use of contrast agents. The high sensitivity of SWI relative to other imaging techniques in showing tumor vasculature and microhemorrhages suggests that it is an effective imaging modality that provides additional information not shown using conventional MRI. Despite SWI's clinical advantages, its implementation in MRI protocols is st...

show abstract

“…The postprocessing of the perfusionweighted raw images was performed by a specific software, Signal Processing In NMR (SPIN, The MRI Institute for Biomedical Research, Detroit, USA). 25 Deconvolution with singular value decomposition was used to create quantitative maps of mean transit time (MTT), CBF, and CBV. The position of the arterial input function was automatically determined by using the maximum concentration (Cmax), relative time to peak (TTP), and first moment MTT (fMTT).…”

Section: Postprocessingmentioning

confidence: 99%

Perfusion-weighted imaging and dynamic 4D angiograms for the estimation of collateral blood flow in lacunar infarction

Förster

Mürle

Böhme

et al. 2016

J Cereb Blood Flow Metab

View full text Add to dashboard Cite

Although lacunar infarction accounts for approximately 25% of ischemic strokes, collateral blood flow through anastomoses is not well evaluated in lacunar infarction. In 111 lacunar infarction patients, we analyzed diffusion-weighted images, perfusion-weighted images, and blood flow on dynamic four-dimensional angiograms generated by use of Signal Processing In NMR-Software. Blood flow was classified as absent (type 1), from periphery to center (type 2), from center to periphery (type 3), and combination of type 2 and 3 (type 4). On diffusion-weighted images, lacunar infarction was found in the basal ganglia (11.7%), internal capsule (24.3%), corona radiata (30.6%), thalamus (24.3%), and brainstem (9.0%). In 58 (52.2%) patients, perfusion-weighted image showed a circumscribed hypoperfusion, in one (0.9%) a circumscribed hyperperfusion, whereas the remainder was normal. In 36 (62.1%) patients, a larger perfusion deficit (>7 mm) was observed. In these, blood flow was classified type 1 in four (11.1%), 2 in 17 (47.2%), 3 in 9 (25.0%), and 4 in six (16.7%) patients. Patients with lacunar infarction in the posterior circulation more often demonstrated blood flow type 2 and less often type 3 (p ¼ 0.01). Detailed examination and graduation of blood flow in lacunar infarction by use of dynamic four-dimensional angiograms is feasible and may serve for a better characterization of this stroke subtype.

show abstract

Cortical calcification in sturge–weber syndrome on MRI‐SWI: Relation to brain perfusion status and seizure severity

Cited by 60 publications

References 28 publications

The Many Faces of Cerebral Developmental Venous Anomaly and Its Mimicks: Spectrum of Imaging Findings

The Many Faces of Cerebral Developmental Venous Anomaly and Its Mimicks: Spectrum of Imaging Findings

Magnetic resonance susceptibility weighted imaging in neurosurgery: current applications and future perspectives

Perfusion-weighted imaging and dynamic 4D angiograms for the estimation of collateral blood flow in lacunar infarction

Contact Info

Product

Resources

About