Corrole functionalized iron oxide nanocomposites as enhanced peroxidase mimic and their application in H2O2 and glucose colorimetric sensing

Abstract

For the first time, functional Corrole molecules modified iron oxide (Fe 3 O 4) magnetic nanoparticles (MNPs) were prepared by a facile two-step method. The Corrole-Fe 3 O 4 nanocomposites exhibited a higher peroxidase-like activity than that of pure Fe 3 O 4 nanoparticles, and accelerated the oxidation of peroxidase substrate 3,3',5,5'-tetramethylbenzidine (TMB) with the help of hydrogen peroxide (H 2 O 2) only in 5 min, attributing to hydroxyl radicals (•OH) generated in the process of oxidation of TMB. Kinetic analysis showed that the catalytic behaviors followed the typical Michaelis-Menten kinetics. Additionally, Corrole-Fe 3 O 4 exhibits several advantages including low cost, easy separation, facile fabrication, and high catalytic efficiency. Based on the catalytic activity of Corrole-Fe 3 O 4 nanocomposites, a simple, sensitive, and selective colorimetric biosensor for H 2 O 2 and glucose determination was successfully designed. The linear relationships of absorbance of oxidized TMB at 652 nm with H 2 O 2 or glucose concentration were obtained from 10 μM to 100 μM with a detection limit of 3.6 μM and 4 μM to 40 μM with the detection limit as low as 2.46 μM, respectively. The results demonstrate that the Corrole-Fe 3 O 4 nanocomposites have potential applications in bioanalysis and biodetection.

One-Pot Preparation of Imidazole-Ring-Modified Graphitic Carbon Nitride Nanozymes for Colorimetric Glucose Detection

“…As H 2 O 2 is the product of the GO x -catalyzed oxidation of glucose when combined with GO x ( Figure S9 ), the proposed colorimetric strategy was developed for the detection of glucose. As shown in Figure 5 c, the response curve of glucose indicated that the linear relationship ( y = 0.0029* x + 0.0473) of glucose concentration with the absorbance of oxTMB ranged from 0.01 to 100 mM (R 2 = 0.9941), and the detection limit was 10 nM (the signal-to-noise ratio was two, Figure 5 d and Table S3 ), which is more sensitive than that of many other reports [ 31 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 ]. These results indicate that g -C 3 N 4 -Im-Cu exhibits good sensitivity for glucose detection.…”

“…Table S1: Activation energy calculation results; Table S2: Activation energy for H 2 O 2 oxidation catalyzed by different catalysts; Table S3: Limit of detection (LOD) of various nanozymes for glucose. References [ 31 , 46 , 47 , 48 , 49 , 50 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 ] are cited in the supplementary materials.…”

Role of Surfaces in the Magnetic and Ozone Gas-Sensing Properties of ZnFe2O4 Nanoparticles: Theoretical and Experimental Insights

“…Control of morphology, and consequently the material surface, has a great influence on the physicochemical properties of the materials and serves as a powerful way to modulate the functional properties. − To the best of our knowledge, there has been no comprehensive experimental work, supported by theoretical simulations, specifically dealing with surface-dependent sensor and magnetic properties of ZnFe 2 O 4 materials. Inspired by these reports, we aim to bridge the knowledge gap between theoretical and experimental results by preparing ZnFe 2 O 4 NPs with different exposed surfaces.…”

Mechanism of lead pollution detection in soil using terahertz spectrum

“…However, these methods are usually applied in laboratories using advanced instruments (Beauchemin 2008;Darwish and Blake 2001;Kou et al, 2009), which is time-consuming and costly. In contrast, new methods such as electrochemistry have shown their potential applications in different area for portable and rapid applications (Malitesta and Guascito 2005;Xiang et al 2018;Cai et al 2019;Gao et al 2018;Dong et al 2019), but they are still immature for practical use at present for various reasons. Therefore, the development of an efficient, rapid, and accurate method for the detection of heavy metals in soil is urgently needed.…”