Corrigendum to ‘Tandem Fourier transform mass spectrometry of block and random copolymers’ [Int. J. Mass Spectrom. 301 (2011) 184–194]

d-α-tocopheryl Polyethylene Glycol 1000 Succinate: A View from FTICR MS and Tandem MS

“…Several fragments are produced in Figure 6c MS 2 with Different Metallic Cation Adducts. It was reported that different ionization cations can cause complementary fragmentation patterns for multiply charged polymers, 14 so the influence of several metallic-cationizing agents are investigated. Apart from sodium, lithium and silver are chosen for this study, because lithium is the most reactive metal and the smallest alkali metal, whereas silver typically bonds to a π bonded region.…”

“…A high performance mass spectrometry combined with tandem mass spectrometry (MS/MS) technique is a valuable tool in the study of polymer structures because it has been successfully used in obtaining structural information for many categories of compounds. 6−11 Study of polymers using high performance mass spectrometry to determine their mass distribution and absolute molar masses, 12 end-groups and polymerization mechanisms, 13 structure and compositions 14,15 are common areas of research. Combining LC/MS and FTICR MS/MS was employed in the end-group study of methacrylic polymers, where the remarkable mass accuracy and resolution of a FTICR MS instrument demonstrated its utility in studying complex synthetic polymer systems.…”

“…13 By using FTICR MS with both electron capture dissociation (ECD) and collisionally activated dissociation (CAD), Kaczorowska and Cooper reported the structural characterization of polyphosphoesters, and their MS/MS degradation pathways were discussed. 16 Most recently, a better understanding of the composition and variability of two commonly used polymeric excipients, Gelucire 44/14 and polysorbate 80, between batches were achieved aided by the high mass accuracy of FTICR MS. 17 However, tandem mass spectrometry employed in the structural characterization of synthetic polymers is still underdeveloped, due to difficulties involved in fragmenting diverse, and often stable, polymer bonds between monomer units 14 and distinct data analysis strategies associated with different polymer classes.…”