Corrigendum to “Protective Effects of a Polyphenol-Rich Extract from <i>Syzygium cumini</i> (L.) Skeels Leaf on Oxidative Stress-Induced Diabetic Rats”

Chagas, Vinicyus Teles; Coelho, Rafaella Moraes Rego de Sousa; Gaspar, Renato Simões; Silva, Samira Abdalla da; Mastrogiovanni, Mauricio; Mendonça, Cáritas de Jesus Silva; Ribeiro, Maria Nilce de Sousa; Paes, Antonio Marcus de Andrade; Trostchansky, Andrés

doi:10.1155/2019/5785798

Cited by 5 publications

(6 citation statements)

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“…The ABTS solution was prepared in water and potassium persulfate and kept in the dark room for 16 h before testing for the complete oxidation of ABTS •+ and the generation of the highly stable chromophore cation radical 2,2′–azino–bis(3 ethylbenzothiazoline–6–sulfonic acid) (ABTS •+ ) [58] with [59] modifications. The ABTS •+ solution was diluted with 70% ethanol/water (70:30, v / v ) until the absorbance at 734 nm reached 0.7 ± 0.02.…”

Section: Methodsmentioning

confidence: 99%

Anti-Inflammatory and Antinociceptive Activity of Pollen Extract Collected by Stingless Bee Melipona fasciculata

Lopes

Vasconcelos

Pereira

et al. 2019

IJMS

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The stingless bee, Melipona fasciculata Smith (Apidae, Meliponini), is a native species from Brazil. Their products have high biotechnological potential, however there are no studies about the biological activities of pollen collected by M. fasciculata. In this context, the present study investigated the chemical composition, anti-oxidant, anti-inflammatory, and analgesic activities of hydroethanolic pollen extracts collected by M. fasciculata in three cities in Maranhão State, Brazil. We verified the antioxidant activity of the extracts and inhibitory activity against the cyclooxygenase enzyme using in vitro assays and in allowed to select the extract with higher efficiency to be used on in vivo assays. In these trials, the selected extract showed high anti-inflammatory activity as well as nociceptive effects at central and peripheral level, suggesting that this extract acts on inhibition of histamine release and decreased synthesis of prostaglandins and the in-silico study suggested that polyphenols and acids fatty acids in the extract may be associated with these activities. The results of the present study report the high biological potential of pollen extract and we conclude that the pollen collected by M. fasciculata can be considered as the object of research for new pharmacological alternatives.

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Section: Methodsmentioning

confidence: 99%

Anti-Inflammatory and Antinociceptive Activity of Pollen Extract Collected by Stingless Bee Melipona fasciculata

Lopes

Vasconcelos

Pereira

et al. 2019

IJMS

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show abstract

“…The ABTS solution was prepared in water and potassium persulfate and kept in the dark room for 16 h before testing for the complete oxidation of ABTS •+ and the generation of the highly stable chromophore cation radical 2,2 -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS •+ ) [18] with modifications [19]. The ABTS •+ solution was diluted with 70% ethanol/water (70:30, v/v) until the absorbance at 734 nm reached 0.7 ± 0.02, like was described in [7].…”

Section: Abts •+ Assaymentioning

confidence: 99%

Anti-Inflammatory and Antioxidant Activity of Pollen Extract Collected by Scaptotrigona affinis postica: in silico, in vitro, and in vivo Studies

et al. 2020

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Bees are of great importance for plant diversity for being an important pollinating agents. Stingless bees such as Scaptotrigona affinis postica, is cultivated largely due to the products offered by it. Pollen is one of these products, which has been highlighted for exhibit various therapeutic properties. Considering the bioactivity of this natural product, this study investigated the antioxidant, anti-inflammatory, antinociceptive activities, and elucidated the chemical composition of pollen collected extract by Scaptotrigona affinis postica. Using in vitro assays, the antioxidant potential and inhibitory activity against the COX enzyme from pollen extract was evaluated. Additionally, tests were performed to measure the anti-inflammatory and antinociceptive activities in animal models. In our results, we found that pollen extract showed antioxidant effects and inhibitory activity against the COX enzyme. The in vivo assays showed that the extract acts on the nervous system in local and systemic levels and that the anti-inflammatory activity is due the prostanoids reducing. Chemical analyses recognize 10 molecules in the extract belonging to the polyphenol and flavonoids classes and the computational study suggests that is responsible for the observed results. Thus, it is reported for the first time the biological potential of S. aff. postica pollen extract and we conclude that this bee product can be considered as one source of potential new drugs.

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“…20,36 According to another study, Syzygium cumini leaf extract contains quercetin, myricetin, kaempferol, and glycosides. 37 Because of the high antioxidant content of Syzygium cumini leaf extract, Malondialdehyde levels are reduced, and catalase activity was raised, thus diminishing oxidative stress.…”

Section: Discussionmentioning

confidence: 99%

“…Reactive oxygen species can be neutralized by exogenous antioxidants acquired from medicinal plants. 37…”

Section: Discussionmentioning

confidence: 99%

Syzygium Cumini Leaves Extract from West Sumatra Indonesia Alleviate Oxidative Stress by Decreasing Malondialdehyde Level and Enhancing Catalase Activity in Rat Induced by Lead Acetate

Rita¹,

Sy²

2021

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Corrigendum to “Protective Effects of a Polyphenol-Rich Extract from Syzygium cumini (L.) Skeels Leaf on Oxidative Stress-Induced Diabetic Rats”

Cited by 5 publications

References 1 publication

Anti-Inflammatory and Antinociceptive Activity of Pollen Extract Collected by Stingless Bee Melipona fasciculata

Anti-Inflammatory and Antinociceptive Activity of Pollen Extract Collected by Stingless Bee Melipona fasciculata

Anti-Inflammatory and Antioxidant Activity of Pollen Extract Collected by Scaptotrigona affinis postica: in silico, in vitro, and in vivo Studies

Syzygium Cumini Leaves Extract from West Sumatra Indonesia Alleviate Oxidative Stress by Decreasing Malondialdehyde Level and Enhancing Catalase Activity in Rat Induced by Lead Acetate

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