Corrigendum to “Heparan sulfate analogues regulate tumor-derived exosome formation that attenuates exosome functions in tumor processes” [Int. J. Biol. Macromol. 187 (2021) 481–491]

Wu, Xiao‐Tao; Kang, Mingzhu; Wang, Danhui; Zhu, Min; Hu, Yiwei; Zhang, Yan; Deng, Chao; Chen, Jinghua; Teng, Liping

doi:10.1016/j.ijbiomac.2021.10.151

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Exosome Biogenesis1

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“…34 The physiological significance of syndecan heparan sulfate proteoglycans has been demonstrated in the regulation of Exo biogenesis. 35 ALIX interacts directly with LYPX (n) L motifs of syntenin as a cytoplasmic adaptor of syndecans. 32 The explained interaction leads to N-linked glycosylation, which causes sorting of the glycoprotein into MVBs, suggesting that Exo are formed from both the plasma membrane and endosomal pathways, not just the endosome.…”

Section: Exosome Biogenesismentioning

confidence: 99%