Corrigendum: 3D-Printed Poly-Caprolactone Scaffolds Modified With Biomimetic Extracellular Matrices for Tarsal Plate Tissue Engineering

Polymers and Biomaterials for Posterior Lamella of the Eyelid and the Lacrimal System

“…Recent studies have also explored the use of synthetic polymers, including porous polyethylene (PE) [90,96], poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) [97], poly(lactic-co-glycolic) acid (PLGA) [98][99][100], and PCL [101] for tarsal plate reconstruction. Among these, only high-density porous PE (Medpor ® ) has been clinically leveraged as an eyelid spacer to address lower eyelid retraction.…”

“…Consequently, recent progress is centered on developing cellular grafts that aim to fully reinstate both the structural integrity and functional aspects of the posterior lamellar. This innovative approach involves seeding bioscaffolds with cells that replicate desired tissue functions, subsequently facilitating transplantation to foster tissue regeneration [71,99,101].…”

Sebaceous gland: Milestones of 30‐year modelling research dedicated to the “brain of the skin”

“…[96] More recently, the long-term expansion of epidermal stem cells in spheroids and organoids [50,64,65] promises a more efficient culture method for human epidermal stem cells. Meanwhile, current culture methods for SKP are not equally efficient, [97] and new technologies, such as 3D-printed scaffolds modified with biomimetic extracellular matrices, [98] to improve the proliferation and long-term epigenetic stability of the cells, and microfluidic platforms/organ-on-a-chip technology [99] are crucial.…”

“…Furthermore, patient-specific 3D culture models and SKP may open new perspectives in understanding the genetic basis of skin diseases and in a therapeutic context in the field of personalized medicine. [50,64,80] In the future, such 3D systems could be combined with new scaffold technologies [98] and microfluidic platforms [99] allowing precise control and measurement of different culture parameters.…”

“…Nelson et al [49] demonstrated transient immortalization of primary sebocytes with a Rho kinase inhibitor 2016 Wang et al [80] combined culture-expanded epidermal stem cells and skin-derived progenitors from adult humans and obtain de novo regeneration of functional hair follicles and sebaceous glands 2020 Chen et al [98] applied 3D printing technology to fabricate tarsal plate scaffolds using poly-caprolactone, which coated with decellularized matrix of adipose-derived mesenchymal stromal cells and SZ95 sebocytes obtaining biocompatibility of the coated scaffolds as well as sebocyte proliferation and lipogenesis…”