Abstract:Background: One of the central features of the immune system is the capacity to mount an inammatory response to potentially harmful foreign
materials while avoiding damage to self-tissues. Autoimmunity is dened as an immune response leading to reaction with self-antigen, this may be
a harmless phenomenon, identied only by the presence of low-titre autoantibodies or autoreactive T cells. These are a major cause of chronic
morbidity and disability, affecting up to 1 in 30 adults at some point during life. Aut… Show more
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