Abstract.A concept of reactive hot spots intruded in a thick, structural reactive material casing was investigated to generate fine fragments for efficient energy release from casing material under explosive loading. This was achieved through distributing micro MoO 3 particles into a granular Al casing, made by hot isostatic pressing, in a fuel-rich ratio of 10Al+MoO 3 . Reaction of Al and MoO 3 during casing primary or secondary fragmentation creates heat and gas products to form micro-scale hot spots, whose expansion initiates local fractures leading to fine fragments of the rest of Al. Explosion experiments, using a 4.4 cm diameter cased charge with a casing-to-explosive mass ratio of 1.78 in a 2.1 m 3 cylindrical chamber, demonstrated the presence of fine fragments and more efficient fragment combustion to augment air blast, as compared to a baseline pure Al-cased charge, thus indicating the feasibility of the concept.