Correlation of neurologic assessment in the preterm newborn infant with outcome at 1 year

Dubowitz, Lilly; Dubowitz, Victor; Palmer, Penelope; Miller, Geoffrey; Fawer, C. L.; Levene, M I

doi:10.1016/s0022-3476(84)80028-1

Cited by 90 publications

(37 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The most likely explanation was periventric ular ischemia not recognizable in immature infants with the currently available cerebral imaging techniques. Ventricular dilatation can result in tissue injury; it can be associated with axonal swelling and tissue disruption in the periventricular regions of the brain [14], Furthermore, many hypoxic insults may re sult in other types of brain injury that may not be detected by noninvasive cranial imag ing techniques [7], Our data support the ob servations of others [8], that the most impor tant factor in determining neurologic out come is the extent of the hemorrhage. The development of progressive ventricular dila tation may only contribute to the extent of brain injury.…”

Section: Discussionsupporting

confidence: 83%

Neurological Prognosis of High-Risk Preterm Infants with Peri-Intraventricular Hemorrhage and Ventricular Dilatation

Amato¹,

Howald²,

Muralt³

1986

Eur Neurol

View full text Add to dashboard Cite

Fifty-eight preterm neonates evaluated by real-time sonographic scanning of the head were prospectively studied. They were divided into three groups: 13 with peri-intraven-tricular hemorrhage (PIVH) alone, 19 with subsequent ventricular dilatation and 26 control infants without ultrasound evidence of PIVH. At 12 months of age detailed neurological follow-up assessment was carried out. Five (8.6%) patients had major handicaps, 34 minor neurological abnormalities. The severity of the PIVH correlated with the neurologic outcome (p < 0.02). The incidence of major handicaps was significantly greater in the group with ventricular dilatation (p < 0.03). Among the infants with PIVH, major handicaps were only present if associated with grade III and IV. Severe posthemorrhagic ventricular dilatation increased the risk for major handicaps. Adverse neurological sequelae at follow-up appeared to be attributable to the extent of PIVH and aggravated by severe ventricular enlargement.

show abstract

Section: Discussionsupporting

confidence: 83%

Neurological Prognosis of High-Risk Preterm Infants with Peri-Intraventricular Hemorrhage and Ventricular Dilatation

Amato¹,

Howald²,

Muralt³

1986

Eur Neurol

View full text Add to dashboard Cite

show abstract

“…Our findings agree with those related by Dubowitz et al 4 , and Anderson et al 8 , mainly trunk hypotonia and abnormal head control. A greater upper extremities flexor tonus involvement in relation to lower extremities is indicative of pyramidal tract involvement 9,11 .…”

Section: Discussionsupporting

confidence: 94%

Neurological evaluation of neonates with intraventricular and periventricular hemorrhage

Sanchez-Stopiglia

Moura-Ribeiro

Marba

1999

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-We studied the clinical aspects of 100 consecutive premature newborns with and without intraventricular and periventricular hemorrhage (IPVH).The diagnosis of IPVH was obtained by ultrasonic scans of the skull during the first week of life and at the age of one month. Forty eight percent of newborns with IPVH had abnormal results, and there was a significant correlation with the neurological evaluation in 85% of the infants. The probability of normality for a child with no associated brain abnormalities was 72%, whereas for a child of the same gestational age with associated brain abnormalities was 48.7%.KEY WORDS: intraventricular and periventricular hemorrhage, neonate, premature newborn, cranial ultrasound. Avaliação neurológica de recém-nascidos com hemorragia intraventricular e periventricularRESUMO -Foram estudados os aspectos clínicos de 100 recém-nascidos prematuros, com e sem hemorragia periventricular-intraventricular (HPIV). O diagnóstico foi obtido através de exames ultra-sonográficos de crânio, realizados durante a primeira semana de vida e na idade corrigida de um mês.Quarenta e oito por cento dos recém-nascidos com HPVI evidenciaram resultados anormais, sendo a correlação significativa com a evolução neurológica, em 85% das crianças. Crianças que não apresentaram anormalidades cerebrais associadas tiveram 72% de probabilidade de manter a evolução normal, enquanto para crianças da mesma idade gestacional porém com anormalidades cerebrais associadas, a probabilidade foi 48,7%. PALAVRAS-CHAVE :hemorragia intraventricular e periventricular, recém-nascido, prematuro, ultrasom craniano.

show abstract

“…Cerebral injury may result from intraventricular hemorrhage, which occurs in 35-50% of premature infants [1 , 2], and from hypoxic-ischemic cerebral insults [3][4][5][6][7][8][9].…”

mentioning

confidence: 99%

MR imaging of periventricular leukomalacia in childhood

Flodmark

Lupton

et al. 1989

American Journal of Roentgenology

View full text Add to dashboard Cite

Correlation of neurologic assessment in the preterm newborn infant with outcome at 1 year

Cited by 90 publications

References 14 publications

Neurological Prognosis of High-Risk Preterm Infants with Peri-Intraventricular Hemorrhage and Ventricular Dilatation

Neurological Prognosis of High-Risk Preterm Infants with Peri-Intraventricular Hemorrhage and Ventricular Dilatation

Neurological evaluation of neonates with intraventricular and periventricular hemorrhage

MR imaging of periventricular leukomalacia in childhood

Contact Info

Product

Resources

About