Correlation of Fine Needle Aspiration Cytology with Histopathology of Malignant Breast Lesions in a Tertiary Care Hospital- Mandya

Siddegowda, M S; Ara, Tahniyat

doi:10.18410/jebmh/2019/559

Cited by 2 publications

(2 citation statements)

References 11 publications

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“…The incidence of breast malignancy has increased worldwide due to advancement in screening, diagnosis and changes in life style of women. 6 Early detection and screening can decrease breast carcinoma mortality around 18-29%. 13 FNAC of palpable breast lumps is a well accepted and established diagnostic tool for determining the benign or malignant breast lesions with high degree of accuracy.…”

Section: Discussionmentioning

confidence: 99%

“…5 It helps in differentiating malignant from benign breast lesions, and it plays an important role in Triple test along with clinical and mammography examination in assessment of breast lumps. 6 Mammography is other screening diagnostic modality for a breast lump which is routinely used method with simple, low cost with high accuracy. 3 Benign breast lesions are round to oval in shape with regular, linear margin, homogenous echo texture and hypoechoic.…”

Section: Introductionmentioning

confidence: 99%

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Correlation of FNAC with Histopathology of breast lesions

Risaldar¹,

Begum²,

Alvi³

2020

JDPO

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Breast cancer is a commonest maliganancy of women globally. A papable breast lump is common diagnostic dilemma to surgeons. Fine needle aspiration cytology (FNAC) is simple rapid, accurate diagnostic tool for evaluating palpable breast lumps. Mammography is other screening modality for a breast lump which is routinely used method with simple, low cost with high accuracy. Aim: To differentiate and categories the breast lesions, and to study the correlation of FNAC with histopathology of palpable breast lumps.Materials and Methods: one and half year retrospective study carried out from January 2019 to June 2020 in the department of pathology, KBNIMS, Gulbarga. FNAC and Histopathology slides were retrieved and reviewed. All the slides were observed and findings recorded. Mammography findings were retrieved and recorded.Result: The present study includes 125 cases out of which 101 cases (80.8%) were benign and 24 cases (19.2%) were malignant. Most common benign breast lesion was fibroadenoma (52.4%) and malignant lesion was infiltrating ductal carcinoma (75%). Frequencies of left breast lesions were high compare to right breast lesions. Out of 125 cases FNAC, 123 cases (98.4%) correlated with histopathology with sensitivity of 91.66%, specificity of 100%, positive predictive value (PPV) of 100%, negative predictive value (NPV) of 98% and accuracy of 98.4%.Out of 125 cases, mammography of 25 cases were retrieved with sensitivity of 87.5% and specificity of 94.11% with diagnostic accuracy of 92%. Conclusion: FNAC is a valuable diagnostic tool; provide rapid and reliable diagnosis in breast lesions.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Correlation of FNAC with Histopathology of breast lesions

Risaldar¹,

Begum²,

Alvi³

2020

JDPO

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Cytopathological Patterns of Palpable Breast Lumps on Fine Needle Aspiration - A Hospital Based Study

Kumbhakar¹,

Talukdar²

2021

jebmh

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BACKGROUND The breast is composed of both specialised epithelial cells and stroma. Both benign and malignant lesions can occur in the breast as a palpable lump. Fine needle aspiration cytology (FNAC) is a rapid, easy to perform, minimally invasive and low cost first line high-diagnostic accuracy test for cytopathological evaluation of palpable breast lump with minimum complications. METHODS The study was carried out to evaluate the cytopathological patterns of 2706 palpable breast lumps by fine needle aspiration (FNA) procedure and cytohistopathological correlation of the available biopsied palpable breast lumps of the study in the Pathology department of Tezpur Medical College and Hospital, Assam, for a period of three years from July 01, 2016 to June 30, 2019. RESULTS Out of 2706 palpable breast lumps in the study, FNA smears of 19 (0.70 %) were inadequate for cytopathological reporting. Out of the remaining 2687 palpable breast lumps where FNA was adequate for cytopathological reporting, female patients (n = 2594) comprised 96.54 % and male patients (n = 93) comprised 3.46 % with a male and female ratio of 1:27.9. Out of the 2687 palpable breast lumps, 2318 were benign breast diseases (86.27 %) and 369 were malignant neoplasms (13.73 %), with a benign and malignant ratio of 6.28:1. Out of the benign breast lumps, fibroadenoma breast was seen in 1228 (52.98 %) and of the malignant neoplasms, infiltrating duct carcinoma was seen in 341 (92.41 %). Cytohistopathological correlation showed 98.70 % sensitivity, 99.38 % specificity, 99.35 % positive predictive value, 98.76 % negative predictive value, and 99.04 % diagnostic accuracy. CONCLUSIONS FNAC has high sensitivity and specificity in cytopathological diagnosis of palpable breast lumps. Based on the accurate cytopathological diagnosis of the palpable breast lumps, patients with palpable breast lumps can be given adequate treatment. KEYWORDS Fibroadenoma, Gynaecomastia, Duct Papilloma, Infiltrative Duct Carcinoma, Medullary Carcinoma, Mucinous Carcinoma, Malignant Phyllodes

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Correlation of Fine Needle Aspiration Cytology with Histopathology of Malignant Breast Lesions in a Tertiary Care Hospital- Mandya

Cited by 2 publications

References 11 publications

Correlation of FNAC with Histopathology of breast lesions

Correlation of FNAC with Histopathology of breast lesions

Cytopathological Patterns of Palpable Breast Lumps on Fine Needle Aspiration - A Hospital Based Study

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