Correlation of Extract Composition on Antioxidant Activity of Electrospun PolyvinylPyrrolidone/&lt;i&gt;Bassela rubra linn&lt;/i&gt; Leaf Extract Composite

Septiani, Eka Lutfi; Gabriel, Azmi Alvian; Prastuti, Okky Putri; Indahsari, Defi Nur; Ariyanti, Ervina Diah; Machmudah, Siti; Winardi, Sugeng; Diono, Wahyu; Kanda, Hideki; Goto, Motonobu

doi:10.4028/www.scientific.net/kem.851.122

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…Viskositas larutan polimer yang akan diinjeksikan pada elektrospinning harus cukup tinggi, secara visual larutan tampak seperti gel. Untuk menentukan viskositas larutan polimer yang tepat untuk dapat menghasilkan serat nano secara optimal, secara sederhana diindikasikan dengan terbentuknya Taylor Cone di ujung spinneret saat elektrospinning [10,11]. Taylor cone yang terbentuk dengan konsentrasi EBRL sebesar 2%, 5%, dan 8% bergerak secara non-aksial.…”

Section: Analisis Bentuk Taylor Coneunclassified

Sintesis Nanofiber PVP dengan Ekstrak Basella rubra Linn. Menggunakan Metode Elektrospinning

et al. 2021

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Pembalut luka alternatif dari lembaran serat nano telah dikembangkan baru-baru ini. Aktivitas antioksidan dan antibakteri berperan penting dalam proses penyembuhan luka. Penelitian ini bertujuan untuk menggabungkan sifat ekstrak Bassela rubra Linn. (EBRL) menjadi serat nano polivynil pyrrolidone (PVP) dengan metode elektrospinning. Langkah pertama yang dilakukan adalah menimbang Bassela rubra L. sebanyak 8 gram dan membungkus kedalam kertas saring. Kemudian diekstraksi dengan menggunakan etanol 99% sebagai pelarut pada suhu ± 78 oC. Langkah selanjutnya adalah membuat nanofiber dengan metode elektrospinning dengan menimbang PVP (Polivinil pirrolidon) sebanyak 8%wt. Menambahkan ekstrak Bassela rubra L. sebanyak 2%wt, 5%wt dan 8%wt pada larutan kedalam jarum suntik. Lalu mengatur laju alir 1 mL/jam, jarak antara spineret dengan kolektor 10 cm, dan tegangan 12kV. Dalam pengaplikasian nanofiber dengan EBRL diperlukan ukuran serat tertentu, maka dalam penelitian ini dilakukan pengamatan dampak komposisi EBRL terhadap diameter dan distribusinya. Metode ini dimulai dengan menginjeksikan larutan PVP dan EBRL dengan berbagai komposisi menuju kolektor dalam seperangkat alat elektrospinning. Morfologi nanopartikel telah dianalisa menggunakan metode Scanning Electron Microscopy (SEM). Perbedaan komposisi EBRL memberikan diameter dan distribusi diameter yang berbeda-beda. Hal ini dapat dipengaruhi oleh bentuk Taylor Cone dari larutan yang diinjeksikan.An alternative wound dressing based on nanofiber mats have been developed recently. The antioxidant and antibacterial activity play an important role in wound healing process. This study aims to combine the properties of Bassela rubra Linn. (EBRL) extract into polivynil pyrrolidone (PVP) nanofibers using the electrospinning method. The first step is to weigh 8 grams of basella rubra linn and wrap it in filter paper. Then extracted using 99% ethanol as a solvent at a temperature of ± 78 oC. The next step is to make nanofibers using the electrospinning method by weighing 8% wt of PVP (Polyvinyl pyrrolidone). Basella rubra linn extract as much as 2% wt, 5% wt and 8% wt in the solution into a syringe. Then assistance with the flow rate of 1 mL / hour, the distance between the spineret and the collector is 10 cm, coating the collector with aluminum foil, and providing 12kV voltage assistance. In the application of nanofibers with EBRL, a certain fiber size is required, so in this study, we observed the impact of EBRL on its diameter and distribution. This method begins by injecting PVP and EBRL solutions of various compositions into the collector in a set of electrospinning devices. The morphology of the nanoparticles was analyzed using the Scanning Electron Microscopy (SEM) method. Differences in the composition of EBRL provide different diameter and diameter distribution. This can be constructed by the Taylor Cone form of the solution that is injected.

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Section: Analisis Bentuk Taylor Coneunclassified

Sintesis Nanofiber PVP dengan Ekstrak Basella rubra Linn. Menggunakan Metode Elektrospinning

et al. 2021

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Phenolic Compound, Antioxidant and Antibacterial properties of Electrospun PVP Nanofiber loaded with Bassela rubra linn extract and Alginate from Sargassum sp.

Septiani

Prastuti

Machmudah

et al. 2021

IOP Conf. Ser.: Mater. Sci. Eng.

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An alternative wound dressing based on nanofiber mats have been developed recently. The antioxidant and antibacterial activity play an important role in wound healing process. This study aims to combine the properties of Bassela rubra linn extract (BRLE) and Alginate from brown macroalgae into Polivynil Pyrrolidone (PVP) nanofiber using electrospinning method. Firstly, the optimization step was conducted to obtain the best operation voltage and distance. Afterwards, the nanofiber composites of PVP/BRLE/Alginate were injected into electrospinning tool in various Alginate concentrations of 1%, 2%, and 3% (w/w) respectively. The morphology of PVP nanofiber observed by Scanning Electron Microscopy (SEM) conveys that the closest distance and the highest voltage were the best. Meanwhile, the in vitro analysis through 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and antibacterial activity to S. aureus and E. choli bacteria show a quite strong radical scavenging ability around 60% and adequate antibacterial property as good as reference a well-known material consecutively.

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Correlation of Extract Composition on Antioxidant Activity of Electrospun PolyvinylPyrrolidone/<i>Bassela rubra linn</i> Leaf Extract Composite

Cited by 2 publications

References 15 publications

Sintesis Nanofiber PVP dengan Ekstrak Basella rubra Linn. Menggunakan Metode Elektrospinning

Sintesis Nanofiber PVP dengan Ekstrak Basella rubra Linn. Menggunakan Metode Elektrospinning

Phenolic Compound, Antioxidant and Antibacterial properties of Electrospun PVP Nanofiber loaded with Bassela rubra linn extract and Alginate from Sargassum sp.

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