Correlation of Contrast-Enhanced Ultrasonographic Features with Microvessel Density in Papillary Thyroid Carcinomas

Contrast‐Enhanced Ultrasound Differentiation Between Low‐ and High‐ Grade Bladder Urothelial Carcinoma and Correlation With Tumor Microvessel Density

“…However, determining MVD requires surgical and biopsy specimens that are prone to sampling errors. Thus, it is essential to establish a noninvasive in vivo assay for estimating tumor vessels, which samples the entire tumor and is repeatable at frequent intervals …”

“…Thus, it is essential to establish a noninvasive in vivo assay for estimating tumor vessels, which samples the entire tumor and is repeatable at frequent intervals. 11 The recent rapid development of contrast-enhanced ultrasound (CEUS) has increased the clinical value of ultrasound in oncology by providing quantification of tumor blood perfusion parameters. 12 It has already been suggested that CEUS has the potential for differentiating low-grade bladder urothelial carcinoma from high grade.…”

Thyroid Ultrasound: State of the Art. Part 2 – Focal Thyroid Lesions

“…Compared with the peripheral parenchyma, 60 PTC nodules showed low heterogeneous enhancement and 2 nodules showed slightly high enhancement, and the peak intensity of CEUS in PTC was lower than in peripheral parenchyma [51].…”

Predicting lymph node metastasis in patients with papillary thyroid carcinoma by vascular index on power Doppler ultrasound

“…Color Doppler ultrasound has been used to calculate tumor vascularity, which is associated with the prognosis of primary cutaneous melanomas . Recently, the use of contrast‐enhanced ultrasonography has been investigated to detect microvessels and its results have been significantly correlated with MVD in patients with thyroid nodules . Unfortunately, contrast‐enhanced ultrasonography is slightly invasive in nature because the dye must be injected, thus, decreasing the merits of it being a noninvasive ultrasound technique.…”

“…10 Recently, the use of contrast-enhanced ultrasonography has been investigated to detect microvessels and its results have been significantly correlated with MVD in patients with thyroid nodules. 11,12 Unfortunately, contrast-enhanced ultrasonography is slightly invasive in nature because the dye must be injected, thus, decreasing the merits of it being a noninvasive ultrasound technique. The vascular index (VI) is a quantitative ultrasound parameter that represents the amount of color in the regions of interest (ROI) and is calculated from the ratio of flow area within the ROI.…”